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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ACSL1
All Species:
19.39
Human Site:
Y21
Identified Species:
35.56
UniProt:
P33121
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P33121
NP_001986.2
698
77943
Y21
E
L
V
D
F
R
Q
Y
V
R
T
L
P
T
N
Chimpanzee
Pan troglodytes
XP_517555
698
77925
Y21
E
L
V
D
F
R
Q
Y
V
R
T
L
P
T
N
Rhesus Macaque
Macaca mulatta
XP_001084069
698
77742
Y21
E
L
V
D
F
R
Q
Y
V
R
T
L
P
T
N
Dog
Lupus familis
XP_848838
698
77922
Y21
E
L
A
D
F
R
Q
Y
V
R
T
L
P
T
N
Cat
Felis silvestris
Mouse
Mus musculus
P41216
699
77905
V22
L
I
D
I
R
Q
Y
V
R
T
L
P
T
N
T
Rat
Rattus norvegicus
P18163
699
78160
V22
L
I
D
I
R
Q
Y
V
R
T
L
P
T
N
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510992
806
89603
F130
E
F
D
D
F
S
Q
F
F
R
S
L
P
A
T
Chicken
Gallus gallus
Q5ZKR7
763
84188
S31
A
Q
G
S
S
E
V
S
L
D
D
I
T
I
N
Frog
Xenopus laevis
Q7ZYC4
739
81601
E39
S
T
P
P
C
Y
A
E
E
T
L
V
Q
P
S
Zebra Danio
Brachydanio rerio
NP_001027007
697
77372
Y21
E
L
D
D
L
R
Q
Y
V
R
S
L
P
T
N
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9V3S9
666
73592
Y22
R
L
R
Q
A
D
A
Y
R
T
T
N
R
Q
D
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9S725
556
60824
Baker's Yeast
Sacchar. cerevisiae
P39518
744
83419
G31
R
L
A
G
Y
T
K
G
S
D
E
Y
I
E
E
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.2
92.9
91.8
N.A.
84.4
85.5
N.A.
58.8
25.1
26.5
69.4
N.A.
26.7
N.A.
N.A.
N.A.
Protein Similarity:
100
99.7
95.9
97.4
N.A.
94.5
94.1
N.A.
72.5
43.6
44.2
83.6
N.A.
45.1
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
93.3
N.A.
0
0
N.A.
46.6
6.6
0
80
N.A.
20
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
93.3
N.A.
13.3
13.3
N.A.
60
20
13.3
86.6
N.A.
26.6
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
20.9
32.2
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
40.2
50.2
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
0
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
16
0
8
0
16
0
0
0
0
0
0
8
0
% A
% Cys:
0
0
0
0
8
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
31
47
0
8
0
0
0
16
8
0
0
0
8
% D
% Glu:
47
0
0
0
0
8
0
8
8
0
8
0
0
8
8
% E
% Phe:
0
8
0
0
39
0
0
8
8
0
0
0
0
0
0
% F
% Gly:
0
0
8
8
0
0
0
8
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
16
0
16
0
0
0
0
0
0
0
8
8
8
0
% I
% Lys:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
0
% K
% Leu:
16
54
0
0
8
0
0
0
8
0
24
47
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
8
0
16
47
% N
% Pro:
0
0
8
8
0
0
0
0
0
0
0
16
47
8
0
% P
% Gln:
0
8
0
8
0
16
47
0
0
0
0
0
8
8
0
% Q
% Arg:
16
0
8
0
16
39
0
0
24
47
0
0
8
0
0
% R
% Ser:
8
0
0
8
8
8
0
8
8
0
16
0
0
0
8
% S
% Thr:
0
8
0
0
0
8
0
0
0
31
39
0
24
39
24
% T
% Val:
0
0
24
0
0
0
8
16
39
0
0
8
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
8
8
16
47
0
0
0
8
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _