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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ACSL1
All Species:
35.45
Human Site:
Y123
Identified Species:
65
UniProt:
P33121
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P33121
NP_001986.2
698
77943
Y123
Q
P
Y
E
W
L
S
Y
K
Q
V
A
E
L
S
Chimpanzee
Pan troglodytes
XP_517555
698
77925
Y123
Q
P
Y
E
W
L
S
Y
K
Q
V
A
E
L
S
Rhesus Macaque
Macaca mulatta
XP_001084069
698
77742
Y123
Q
P
Y
E
W
L
S
Y
K
Q
V
A
E
M
S
Dog
Lupus familis
XP_848838
698
77922
Y123
Q
P
Y
E
W
L
S
Y
K
Q
V
A
E
I
A
Cat
Felis silvestris
Mouse
Mus musculus
P41216
699
77905
Y124
Q
P
Y
E
W
I
S
Y
K
E
V
A
E
L
A
Rat
Rattus norvegicus
P18163
699
78160
Y124
Q
P
Y
E
W
I
S
Y
K
Q
V
A
E
M
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510992
806
89603
Y232
Q
P
Y
Q
W
L
S
Y
K
E
V
A
K
R
A
Chicken
Gallus gallus
Q5ZKR7
763
84188
Y133
G
Q
W
V
K
L
T
Y
K
M
Y
Y
D
K
C
Frog
Xenopus laevis
Q7ZYC4
739
81601
K141
Q
W
H
K
M
S
Y
K
Q
Y
Y
E
Q
C
R
Zebra Danio
Brachydanio rerio
NP_001027007
697
77372
Y123
Q
P
Y
K
W
L
S
Y
K
E
V
A
D
R
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9V3S9
666
73592
A124
S
A
M
G
A
I
H
A
R
G
I
I
A
G
I
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9S725
556
60824
Q87
L
H
N
L
G
V
K
Q
H
D
V
V
M
I
L
Baker's Yeast
Sacchar. cerevisiae
P39518
744
83419
Y133
E
T
F
R
F
E
S
Y
S
T
V
S
K
R
C
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.2
92.9
91.8
N.A.
84.4
85.5
N.A.
58.8
25.1
26.5
69.4
N.A.
26.7
N.A.
N.A.
N.A.
Protein Similarity:
100
99.7
95.9
97.4
N.A.
94.5
94.1
N.A.
72.5
43.6
44.2
83.6
N.A.
45.1
N.A.
N.A.
N.A.
P-Site Identity:
100
100
93.3
86.6
N.A.
80
80
N.A.
66.6
20
6.6
66.6
N.A.
0
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
93.3
40
33.3
93.3
N.A.
20
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
20.9
32.2
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
40.2
50.2
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
20
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
20
53.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
0
0
8
0
0
8
0
0
0
62
8
0
39
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
16
% C
% Asp:
0
0
0
0
0
0
0
0
0
8
0
0
16
0
0
% D
% Glu:
8
0
0
47
0
8
0
0
0
24
0
8
47
0
0
% E
% Phe:
0
0
8
0
8
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
8
0
0
8
8
0
0
0
0
8
0
0
0
8
0
% G
% His:
0
8
8
0
0
0
8
0
8
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
24
0
0
0
0
8
8
0
16
8
% I
% Lys:
0
0
0
16
8
0
8
8
70
0
0
0
16
8
0
% K
% Leu:
8
0
0
8
0
54
0
0
0
0
0
0
0
24
8
% L
% Met:
0
0
8
0
8
0
0
0
0
8
0
0
8
16
0
% M
% Asn:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
62
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
70
8
0
8
0
0
0
8
8
39
0
0
8
0
0
% Q
% Arg:
0
0
0
8
0
0
0
0
8
0
0
0
0
24
8
% R
% Ser:
8
0
0
0
0
8
70
0
8
0
0
8
0
0
24
% S
% Thr:
0
8
0
0
0
0
8
0
0
8
0
0
0
0
0
% T
% Val:
0
0
0
8
0
8
0
0
0
0
77
8
0
0
0
% V
% Trp:
0
8
8
0
62
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
62
0
0
0
8
77
0
8
16
8
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _