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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ACSL1
All Species:
10
Human Site:
T144
Identified Species:
18.33
UniProt:
P33121
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P33121
NP_001986.2
698
77943
T144
L
I
Q
K
G
F
K
T
A
P
D
Q
F
I
G
Chimpanzee
Pan troglodytes
XP_517555
698
77925
T144
L
I
Q
K
G
F
K
T
T
P
D
Q
F
I
G
Rhesus Macaque
Macaca mulatta
XP_001084069
698
77742
A144
L
I
Q
K
G
F
T
A
T
P
D
Q
F
I
G
Dog
Lupus familis
XP_848838
698
77922
T144
L
I
Q
K
G
F
K
T
A
P
D
Q
F
I
G
Cat
Felis silvestris
Mouse
Mus musculus
P41216
699
77905
P145
L
I
Q
K
G
F
K
P
C
S
E
Q
F
I
G
Rat
Rattus norvegicus
P18163
699
78160
P145
L
I
Q
K
G
F
K
P
C
S
E
Q
F
I
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510992
806
89603
P253
L
L
H
H
G
C
K
P
S
S
D
Q
F
I
G
Chicken
Gallus gallus
Q5ZKR7
763
84188
R154
F
L
K
L
V
L
E
R
F
H
G
V
C
I
L
Frog
Xenopus laevis
Q7ZYC4
739
81601
Y162
I
K
L
G
L
E
R
Y
H
G
V
G
I
L
G
Zebra Danio
Brachydanio rerio
NP_001027007
697
77372
Q144
L
L
H
R
G
H
S
Q
S
G
D
K
Y
I
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9V3S9
666
73592
E145
D
A
V
Q
H
V
L
E
S
S
H
A
Q
I
V
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9S725
556
60824
A108
V
V
L
T
F
L
A
A
S
F
I
G
A
I
T
Baker's Yeast
Sacchar. cerevisiae
P39518
744
83419
K154
I
L
S
L
V
N
T
K
R
K
R
P
L
E
A
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.2
92.9
91.8
N.A.
84.4
85.5
N.A.
58.8
25.1
26.5
69.4
N.A.
26.7
N.A.
N.A.
N.A.
Protein Similarity:
100
99.7
95.9
97.4
N.A.
94.5
94.1
N.A.
72.5
43.6
44.2
83.6
N.A.
45.1
N.A.
N.A.
N.A.
P-Site Identity:
100
93.3
80
100
N.A.
73.3
73.3
N.A.
53.3
6.6
6.6
33.3
N.A.
6.6
N.A.
N.A.
N.A.
P-Site Similarity:
100
93.3
80
100
N.A.
80
80
N.A.
66.6
26.6
26.6
66.6
N.A.
20
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
20.9
32.2
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
40.2
50.2
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
26.6
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
0
0
0
0
8
16
16
0
0
8
8
0
8
% A
% Cys:
0
0
0
0
0
8
0
0
16
0
0
0
8
0
0
% C
% Asp:
8
0
0
0
0
0
0
0
0
0
47
0
0
0
0
% D
% Glu:
0
0
0
0
0
8
8
8
0
0
16
0
0
8
0
% E
% Phe:
8
0
0
0
8
47
0
0
8
8
0
0
54
0
0
% F
% Gly:
0
0
0
8
62
0
0
0
0
16
8
16
0
0
70
% G
% His:
0
0
16
8
8
8
0
0
8
8
8
0
0
0
0
% H
% Ile:
16
47
0
0
0
0
0
0
0
0
8
0
8
85
0
% I
% Lys:
0
8
8
47
0
0
47
8
0
8
0
8
0
0
0
% K
% Leu:
62
31
16
16
8
16
8
0
0
0
0
0
8
8
8
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
24
0
31
0
8
0
0
0
% P
% Gln:
0
0
47
8
0
0
0
8
0
0
0
54
8
0
0
% Q
% Arg:
0
0
0
8
0
0
8
8
8
0
8
0
0
0
0
% R
% Ser:
0
0
8
0
0
0
8
0
31
31
0
0
0
0
0
% S
% Thr:
0
0
0
8
0
0
16
24
16
0
0
0
0
0
8
% T
% Val:
8
8
8
0
16
8
0
0
0
0
8
8
0
0
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
8
0
0
0
0
8
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _