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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ACSL1
All Species:
16.67
Human Site:
S78
Identified Species:
30.56
UniProt:
P33121
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P33121
NP_001986.2
698
77943
S78
R
R
S
A
L
L
D
S
D
E
P
L
V
Y
F
Chimpanzee
Pan troglodytes
XP_517555
698
77925
S78
R
R
S
A
L
L
D
S
D
E
P
L
V
Y
F
Rhesus Macaque
Macaca mulatta
XP_001084069
698
77742
S78
R
R
S
A
L
L
D
S
D
E
P
L
V
Y
F
Dog
Lupus familis
XP_848838
698
77922
S78
R
R
S
P
L
L
D
S
D
E
P
L
V
Y
F
Cat
Felis silvestris
Mouse
Mus musculus
P41216
699
77905
D79
R
R
S
A
V
L
E
D
D
K
L
L
V
Y
Y
Rat
Rattus norvegicus
P18163
699
78160
D79
R
R
S
A
V
L
E
D
D
K
L
L
L
Y
Y
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510992
806
89603
S187
R
R
S
V
I
G
G
S
P
K
L
L
T
H
F
Chicken
Gallus gallus
Q5ZKR7
763
84188
L88
Q
Q
D
G
E
V
K
L
R
M
D
E
E
G
M
Frog
Xenopus laevis
Q7ZYC4
739
81601
R96
R
D
S
A
V
K
L
R
L
E
D
S
D
V
A
Zebra Danio
Brachydanio rerio
NP_001027007
697
77372
N78
R
R
S
I
L
M
D
N
D
T
H
M
T
Y
Y
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9V3S9
666
73592
Y79
N
G
Y
H
T
V
T
Y
K
Q
Y
E
Q
K
V
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9S725
556
60824
I42
H
L
P
L
H
D
Y
I
F
E
N
I
S
E
F
Baker's Yeast
Sacchar. cerevisiae
P39518
744
83419
V88
S
E
N
L
V
S
C
V
D
K
N
L
R
T
A
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.2
92.9
91.8
N.A.
84.4
85.5
N.A.
58.8
25.1
26.5
69.4
N.A.
26.7
N.A.
N.A.
N.A.
Protein Similarity:
100
99.7
95.9
97.4
N.A.
94.5
94.1
N.A.
72.5
43.6
44.2
83.6
N.A.
45.1
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
93.3
N.A.
60
53.3
N.A.
40
0
26.6
46.6
N.A.
0
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
93.3
N.A.
86.6
86.6
N.A.
60
20
33.3
73.3
N.A.
13.3
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
20.9
32.2
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
40.2
50.2
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
13.3
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
20
33.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
47
0
0
0
0
0
0
0
0
0
0
16
% A
% Cys:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
0
% C
% Asp:
0
8
8
0
0
8
39
16
62
0
16
0
8
0
0
% D
% Glu:
0
8
0
0
8
0
16
0
0
47
0
16
8
8
0
% E
% Phe:
0
0
0
0
0
0
0
0
8
0
0
0
0
0
47
% F
% Gly:
0
8
0
8
0
8
8
0
0
0
0
0
0
8
0
% G
% His:
8
0
0
8
8
0
0
0
0
0
8
0
0
8
0
% H
% Ile:
0
0
0
8
8
0
0
8
0
0
0
8
0
0
0
% I
% Lys:
0
0
0
0
0
8
8
0
8
31
0
0
0
8
0
% K
% Leu:
0
8
0
16
39
47
8
8
8
0
24
62
8
0
0
% L
% Met:
0
0
0
0
0
8
0
0
0
8
0
8
0
0
8
% M
% Asn:
8
0
8
0
0
0
0
8
0
0
16
0
0
0
0
% N
% Pro:
0
0
8
8
0
0
0
0
8
0
31
0
0
0
0
% P
% Gln:
8
8
0
0
0
0
0
0
0
8
0
0
8
0
0
% Q
% Arg:
70
62
0
0
0
0
0
8
8
0
0
0
8
0
0
% R
% Ser:
8
0
70
0
0
8
0
39
0
0
0
8
8
0
0
% S
% Thr:
0
0
0
0
8
0
8
0
0
8
0
0
16
8
0
% T
% Val:
0
0
0
8
31
16
0
8
0
0
0
0
39
8
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
8
0
0
0
8
8
0
0
8
0
0
54
24
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _