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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ACSL1
All Species:
31.82
Human Site:
S423
Identified Species:
58.33
UniProt:
P33121
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P33121
NP_001986.2
698
77943
S423
I
F
H
K
V
Q
S
S
L
G
G
R
V
R
L
Chimpanzee
Pan troglodytes
XP_517555
698
77925
S423
I
F
H
K
V
Q
S
S
L
G
G
R
V
R
L
Rhesus Macaque
Macaca mulatta
XP_001084069
698
77742
S423
I
F
H
K
V
Q
S
S
L
G
G
K
V
R
L
Dog
Lupus familis
XP_848838
698
77922
S423
I
F
H
K
I
Q
S
S
L
G
G
K
V
R
L
Cat
Felis silvestris
Mouse
Mus musculus
P41216
699
77905
S424
I
F
H
K
I
Q
S
S
L
G
G
K
V
R
L
Rat
Rattus norvegicus
P18163
699
78160
S424
I
F
H
K
I
Q
S
S
L
G
G
K
V
R
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510992
806
89603
S532
F
F
N
K
I
Q
A
S
L
G
G
C
V
R
M
Chicken
Gallus gallus
Q5ZKR7
763
84188
A439
V
Y
K
K
V
R
K
A
I
G
L
D
R
C
T
Frog
Xenopus laevis
Q7ZYC4
739
81601
A445
V
F
K
K
V
R
K
A
L
G
L
D
R
C
T
Zebra Danio
Brachydanio rerio
NP_001027007
697
77372
S422
I
F
S
K
V
Q
A
S
L
G
G
R
V
R
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9V3S9
666
73592
A384
I
M
S
K
V
K
Q
A
L
G
F
D
R
V
L
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9S725
556
60824
T308
A
I
A
K
S
P
E
T
E
K
Y
D
L
S
S
Baker's Yeast
Sacchar. cerevisiae
P39518
744
83419
L456
I
D
K
I
R
D
S
L
G
L
S
N
N
S
F
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.2
92.9
91.8
N.A.
84.4
85.5
N.A.
58.8
25.1
26.5
69.4
N.A.
26.7
N.A.
N.A.
N.A.
Protein Similarity:
100
99.7
95.9
97.4
N.A.
94.5
94.1
N.A.
72.5
43.6
44.2
83.6
N.A.
45.1
N.A.
N.A.
N.A.
P-Site Identity:
100
100
93.3
86.6
N.A.
86.6
86.6
N.A.
60
20
33.3
86.6
N.A.
40
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
86.6
53.3
53.3
93.3
N.A.
53.3
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
20.9
32.2
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
40.2
50.2
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
20
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
8
0
0
0
16
24
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
8
0
16
0
% C
% Asp:
0
8
0
0
0
8
0
0
0
0
0
31
0
0
0
% D
% Glu:
0
0
0
0
0
0
8
0
8
0
0
0
0
0
0
% E
% Phe:
8
70
0
0
0
0
0
0
0
0
8
0
0
0
8
% F
% Gly:
0
0
0
0
0
0
0
0
8
85
62
0
0
0
0
% G
% His:
0
0
47
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
70
8
0
8
31
0
0
0
8
0
0
0
0
0
0
% I
% Lys:
0
0
24
93
0
8
16
0
0
8
0
31
0
0
0
% K
% Leu:
0
0
0
0
0
0
0
8
77
8
16
0
8
0
62
% L
% Met:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
8
% M
% Asn:
0
0
8
0
0
0
0
0
0
0
0
8
8
0
0
% N
% Pro:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
62
8
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
8
16
0
0
0
0
0
24
24
62
0
% R
% Ser:
0
0
16
0
8
0
54
62
0
0
8
0
0
16
8
% S
% Thr:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
16
% T
% Val:
16
0
0
0
54
0
0
0
0
0
0
0
62
8
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
8
0
0
0
0
0
0
0
0
8
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _