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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
FOXN2
All Species:
7.58
Human Site:
S223
Identified Species:
16.67
UniProt:
P32314
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P32314
NP_002149.2
431
47161
S223
L
S
P
H
Y
L
S
S
V
I
K
Q
N
Q
V
Chimpanzee
Pan troglodytes
XP_510111
490
53916
Y225
P
P
T
C
P
Q
A
Y
Q
S
T
S
G
P
P
Rhesus Macaque
Macaca mulatta
XP_001113823
431
47166
S223
L
S
P
H
Y
L
S
S
V
L
K
Q
N
Q
M
Dog
Lupus familis
XP_538485
439
48058
S223
P
A
S
P
Q
S
G
S
L
S
P
H
F
L
S
Cat
Felis silvestris
Mouse
Mus musculus
Q499D0
457
50327
I225
Q
S
T
S
G
P
P
I
W
P
G
S
T
F
F
Rat
Rattus norvegicus
Q63247
421
45548
L215
G
A
F
K
K
R
R
L
P
P
V
H
I
H
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_001034373
180
19794
Frog
Xenopus laevis
Q66J77
430
47078
Y223
T
S
V
S
S
R
P
Y
V
L
T
S
A
S
R
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P32030
322
36184
S116
K
Q
K
M
T
A
G
S
D
T
K
K
P
P
Y
Honey Bee
Apis mellifera
XP_625198
464
52385
N225
R
K
V
E
K
A
P
N
L
G
K
G
S
L
W
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_795496
520
58191
G236
S
P
Y
G
F
S
G
G
P
L
S
N
I
S
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
45.3
98.6
92.4
N.A.
43.3
21.3
N.A.
N.A.
36.6
71.2
N.A.
N.A.
22
25.8
N.A.
31.7
Protein Similarity:
100
58.5
99.5
95.2
N.A.
56.2
35.9
N.A.
N.A.
39.4
81.2
N.A.
N.A.
36.4
41.1
N.A.
46.3
P-Site Identity:
100
0
86.6
6.6
N.A.
6.6
0
N.A.
N.A.
0
13.3
N.A.
N.A.
13.3
6.6
N.A.
0
P-Site Similarity:
100
6.6
100
20
N.A.
6.6
6.6
N.A.
N.A.
0
20
N.A.
N.A.
20
26.6
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
19
0
0
0
19
10
0
0
0
0
0
10
0
0
% A
% Cys:
0
0
0
10
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
10
0
0
0
0
0
0
% D
% Glu:
0
0
0
10
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
10
0
10
0
0
0
0
0
0
0
10
10
10
% F
% Gly:
10
0
0
10
10
0
28
10
0
10
10
10
10
0
0
% G
% His:
0
0
0
19
0
0
0
0
0
0
0
19
0
10
0
% H
% Ile:
0
0
0
0
0
0
0
10
0
10
0
0
19
0
0
% I
% Lys:
10
10
10
10
19
0
0
0
0
0
37
10
0
0
0
% K
% Leu:
19
0
0
0
0
19
0
10
19
28
0
0
0
19
0
% L
% Met:
0
0
0
10
0
0
0
0
0
0
0
0
0
0
10
% M
% Asn:
0
0
0
0
0
0
0
10
0
0
0
10
19
0
0
% N
% Pro:
19
19
19
10
10
10
28
0
19
19
10
0
10
19
19
% P
% Gln:
10
10
0
0
10
10
0
0
10
0
0
19
0
19
0
% Q
% Arg:
10
0
0
0
0
19
10
0
0
0
0
0
0
0
10
% R
% Ser:
10
37
10
19
10
19
19
37
0
19
10
28
10
19
19
% S
% Thr:
10
0
19
0
10
0
0
0
0
10
19
0
10
0
0
% T
% Val:
0
0
19
0
0
0
0
0
28
0
10
0
0
0
10
% V
% Trp:
0
0
0
0
0
0
0
0
10
0
0
0
0
0
10
% W
% Tyr:
0
0
10
0
19
0
0
19
0
0
0
0
0
0
10
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _