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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: OTX2 All Species: 22.42
Human Site: S28 Identified Species: 49.33
UniProt: P32243 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P32243 NP_068374.1 289 31636 S28 G M D L L H P S V G Y P A T P
Chimpanzee Pan troglodytes XP_001163000 296 32257 A35 V G Y P G P W A S C P A A T P
Rhesus Macaque Macaca mulatta NP_001171116 297 32414 A36 V G Y P G P W A S C P A A T P
Dog Lupus familis XP_547830 289 31604 S28 G M D L L H P S V G Y P A T P
Cat Felis silvestris
Mouse Mus musculus P80206 289 31604 S28 G M D L L H P S V G Y P A T P
Rat Rattus norvegicus Q63410 355 37584 S28 A M D L L H P S V G Y P A T P
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus
Frog Xenopus laevis Q6DKN2 289 31671 S28 G M D L L H P S V G Y P A T P
Zebra Danio Brachydanio rerio Q91981 289 31576 S28 G M D L L H P S V G Y P A T P
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P22810 542 55168 Q57 L E A V G F S Q G M W G V N T
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q93356 278 30883 P31 M T M F S G A P Y N A A M I P
Sea Urchin Strong. purpuratus Q26417 371 41197 H121 P M T S E R P H S N G I D P P
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 97.3 96.3 99.3 N.A. 99.6 55.2 N.A. N.A. N.A. 94.4 93.7 N.A. 26 N.A. 31.4 41.2
Protein Similarity: 100 97.3 96.3 99.6 N.A. 100 61.9 N.A. N.A. N.A. 96.8 96.5 N.A. 35.7 N.A. 46.7 51.2
P-Site Identity: 100 20 20 100 N.A. 100 93.3 N.A. N.A. N.A. 100 100 N.A. 0 N.A. 6.6 20
P-Site Similarity: 100 26.6 26.6 100 N.A. 100 93.3 N.A. N.A. N.A. 100 100 N.A. 13.3 N.A. 6.6 20
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 10 0 10 0 0 0 10 19 0 0 10 28 73 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 19 0 0 0 0 0 % C
% Asp: 0 0 55 0 0 0 0 0 0 0 0 0 10 0 0 % D
% Glu: 0 10 0 0 10 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 10 0 10 0 0 0 0 0 0 0 0 0 % F
% Gly: 46 19 0 0 28 10 0 0 10 55 10 10 0 0 0 % G
% His: 0 0 0 0 0 55 0 10 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 10 0 10 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 10 0 0 55 55 0 0 0 0 0 0 0 0 0 0 % L
% Met: 10 64 10 0 0 0 0 0 0 10 0 0 10 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 19 0 0 0 10 0 % N
% Pro: 10 0 0 19 0 19 64 10 0 0 19 55 0 10 91 % P
% Gln: 0 0 0 0 0 0 0 10 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 10 0 0 0 0 0 0 0 0 0 % R
% Ser: 0 0 0 10 10 0 10 55 28 0 0 0 0 0 0 % S
% Thr: 0 10 10 0 0 0 0 0 0 0 0 0 0 73 10 % T
% Val: 19 0 0 10 0 0 0 0 55 0 0 0 10 0 0 % V
% Trp: 0 0 0 0 0 0 19 0 0 0 10 0 0 0 0 % W
% Tyr: 0 0 19 0 0 0 0 0 10 0 55 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _