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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CCKAR All Species: 27.88
Human Site: S417 Identified Species: 61.33
UniProt: P32238 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P32238 NP_000721.1 428 47841 S417 G A S L S R F S Y S H M S A S
Chimpanzee Pan troglodytes XP_526545 428 47894 S417 G A S L S R F S Y S H M S A S
Rhesus Macaque Macaca mulatta XP_001084186 428 47805 S417 G A S L S R F S Y S H M S A S
Dog Lupus familis
Cat Felis silvestris
Mouse Mus musculus O08786 436 48418 S425 R A S L S R Y S Y S H M S T S
Rat Rattus norvegicus P30551 444 49639 S433 R A L L S R Y S Y S H M S T S
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001514193 322 36434 Y312 G S L S R G S Y S H V S I A A
Chicken Gallus gallus NP_001074970 429 48512 S419 R A S L S K C S Y T H M N M S
Frog Xenopus laevis P70031 453 51139 S443 G A S L S K F S Y T T V S S L
Zebra Danio Brachydanio rerio XP_697493 446 49641 T436 S G T L T K L T D T S V R G S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P30974 504 58001 E492 I K Y I S C D E D N N P V E L
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_782630 517 58443 R496 P S Q T S V R R N H P V Q R P
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.5 97.9 N.A. N.A. 88.9 88.2 N.A. 48.3 75.5 52 58 N.A. 23.8 N.A. N.A. 33.2
Protein Similarity: 100 99.5 98.8 N.A. N.A. 92.8 92.5 N.A. 59.5 85.7 68.2 72.1 N.A. 39.8 N.A. N.A. 48.1
P-Site Identity: 100 100 100 N.A. N.A. 80 73.3 N.A. 13.3 60 60 13.3 N.A. 6.6 N.A. N.A. 6.6
P-Site Similarity: 100 100 100 N.A. N.A. 86.6 80 N.A. 26.6 80 86.6 53.3 N.A. 26.6 N.A. N.A. 20
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 64 0 0 0 0 0 0 0 0 0 0 0 37 10 % A
% Cys: 0 0 0 0 0 10 10 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 10 0 19 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 10 0 0 0 0 0 10 0 % E
% Phe: 0 0 0 0 0 0 37 0 0 0 0 0 0 0 0 % F
% Gly: 46 10 0 0 0 10 0 0 0 0 0 0 0 10 0 % G
% His: 0 0 0 0 0 0 0 0 0 19 55 0 0 0 0 % H
% Ile: 10 0 0 10 0 0 0 0 0 0 0 0 10 0 0 % I
% Lys: 0 10 0 0 0 28 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 0 19 73 0 0 10 0 0 0 0 0 0 0 19 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 55 0 10 0 % M
% Asn: 0 0 0 0 0 0 0 0 10 10 10 0 10 0 0 % N
% Pro: 10 0 0 0 0 0 0 0 0 0 10 10 0 0 10 % P
% Gln: 0 0 10 0 0 0 0 0 0 0 0 0 10 0 0 % Q
% Arg: 28 0 0 0 10 46 10 10 0 0 0 0 10 10 0 % R
% Ser: 10 19 55 10 82 0 10 64 10 46 10 10 55 10 64 % S
% Thr: 0 0 10 10 10 0 0 10 0 28 10 0 0 19 0 % T
% Val: 0 0 0 0 0 10 0 0 0 0 10 28 10 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 10 0 0 0 19 10 64 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _