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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
GK
All Species:
13.64
Human Site:
S426
Identified Species:
30
UniProt:
P32189
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P32189
NP_000158.1
559
61245
S426
R
D
C
G
I
P
L
S
H
L
Q
V
D
G
G
Chimpanzee
Pan troglodytes
XP_001150384
553
60623
S420
R
D
C
G
I
P
L
S
H
L
Q
V
D
G
G
Rhesus Macaque
Macaca mulatta
XP_001095944
538
59098
F408
A
A
L
E
A
V
C
F
Q
T
R
E
I
L
D
Dog
Lupus familis
XP_850009
559
61322
S426
R
D
C
G
I
P
L
S
H
L
Q
V
D
G
G
Cat
Felis silvestris
Mouse
Mus musculus
Q64516
559
61209
S426
R
D
C
G
I
P
L
S
H
L
Q
V
D
G
G
Rat
Rattus norvegicus
Q63060
524
57458
F394
T
N
K
C
H
I
A
F
A
A
L
E
A
V
C
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506589
596
65239
F466
T
N
K
N
H
I
A
F
A
A
L
E
A
V
C
Chicken
Gallus gallus
XP_416788
520
57169
A391
K
N
H
I
A
F
A
A
L
E
A
V
C
F
Q
Frog
Xenopus laevis
NP_001080640
563
61588
N427
Q
D
C
G
I
P
L
N
Q
L
Q
V
D
G
G
Zebra Danio
Brachydanio rerio
NP_001108056
530
58172
A398
R
S
H
L
A
F
A
A
L
E
A
V
C
F
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q21944
502
55146
V373
T
I
L
G
L
T
Q
V
T
Q
R
E
H
I
C
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
97.1
96
96.7
N.A.
97.3
91.2
N.A.
78.1
79.7
83.8
75.8
N.A.
N.A.
N.A.
46.5
N.A.
Protein Similarity:
100
97.8
96.2
98.7
N.A.
99.4
92.8
N.A.
84.5
86.7
91.1
84.4
N.A.
N.A.
N.A.
63.5
N.A.
P-Site Identity:
100
100
0
100
N.A.
100
0
N.A.
0
6.6
80
13.3
N.A.
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
100
100
6.6
100
N.A.
100
6.6
N.A.
6.6
26.6
93.3
20
N.A.
N.A.
N.A.
20
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
10
0
0
28
0
37
19
19
19
19
0
19
0
0
% A
% Cys:
0
0
46
10
0
0
10
0
0
0
0
0
19
0
28
% C
% Asp:
0
46
0
0
0
0
0
0
0
0
0
0
46
0
10
% D
% Glu:
0
0
0
10
0
0
0
0
0
19
0
37
0
0
0
% E
% Phe:
0
0
0
0
0
19
0
28
0
0
0
0
0
19
0
% F
% Gly:
0
0
0
55
0
0
0
0
0
0
0
0
0
46
46
% G
% His:
0
0
19
0
19
0
0
0
37
0
0
0
10
0
0
% H
% Ile:
0
10
0
10
46
19
0
0
0
0
0
0
10
10
0
% I
% Lys:
10
0
19
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
19
10
10
0
46
0
19
46
19
0
0
10
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
28
0
10
0
0
0
10
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
46
0
0
0
0
0
0
0
0
0
% P
% Gln:
10
0
0
0
0
0
10
0
19
10
46
0
0
0
19
% Q
% Arg:
46
0
0
0
0
0
0
0
0
0
19
0
0
0
0
% R
% Ser:
0
10
0
0
0
0
0
37
0
0
0
0
0
0
0
% S
% Thr:
28
0
0
0
0
10
0
0
10
10
0
0
0
0
0
% T
% Val:
0
0
0
0
0
10
0
10
0
0
0
64
0
19
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _