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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ATIC All Species: 48.18
Human Site: T329 Identified Species: 96.36
UniProt: P31939 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P31939 NP_004035.2 592 64616 T329 S D V C D V P T A K I I S R E
Chimpanzee Pan troglodytes XP_001150375 592 64537 T329 S D V C D V P T A K I I S R E
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_545634 592 64708 T329 S D I C D V P T A K I I S R E
Cat Felis silvestris
Mouse Mus musculus Q9CWJ9 592 64199 T329 S D I C D V P T A K I I S R E
Rat Rattus norvegicus O35567 592 64190 T329 S D V C D V P T A K I I S R E
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus P31335 593 64396 T330 S D I C D V P T A K I I S R E
Frog Xenopus laevis NP_001090100 589 63809 T327 S D V C D V A T A K I I S R E
Zebra Danio Brachydanio rerio NP_001076265 590 64026 T328 S D V C D V P T A K I I S R E
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_651305 590 63305 T327 S D V C D V V T A R I I S R E
Honey Bee Apis mellifera XP_395924 593 65708 T329 S D T C D E V T A K I I S R E
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_793444 592 64337 T329 S D V C D L P T A K I I S R E
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P38009 592 65245 T328 S N I V D V P T A K I I S R E
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.8 N.A. 94.7 N.A. 91 91.2 N.A. N.A. 83.4 77.5 79.3 N.A. 70.6 68.8 N.A. 68.7
Protein Similarity: 100 99.8 N.A. 98.1 N.A. 95.7 95.6 N.A. N.A. 92.9 92.2 89.8 N.A. 83.2 81.4 N.A. 81.7
P-Site Identity: 100 100 N.A. 93.3 N.A. 93.3 100 N.A. N.A. 93.3 93.3 100 N.A. 86.6 80 N.A. 93.3
P-Site Similarity: 100 100 N.A. 100 N.A. 100 100 N.A. N.A. 100 93.3 100 N.A. 93.3 80 N.A. 100
Percent
Protein Identity: N.A. N.A. N.A. N.A. 61.8 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 76.8 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 80 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 93.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 9 0 100 0 0 0 0 0 0 % A
% Cys: 0 0 0 92 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 92 0 0 100 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 9 0 0 0 0 0 0 0 0 100 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 34 0 0 0 0 0 0 0 100 100 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 92 0 0 0 0 0 % K
% Leu: 0 0 0 0 0 9 0 0 0 0 0 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 9 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 75 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 9 0 0 0 100 0 % R
% Ser: 100 0 0 0 0 0 0 0 0 0 0 0 100 0 0 % S
% Thr: 0 0 9 0 0 0 0 100 0 0 0 0 0 0 0 % T
% Val: 0 0 59 9 0 84 17 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _