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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ATIC
All Species:
25.45
Human Site:
S475
Identified Species:
50.91
UniProt:
P31939
Number Species:
11
Phosphosite Substitution
Charge Score:
0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P31939
NP_004035.2
592
64616
S475
R
H
H
P
Q
V
L
S
M
K
F
K
T
G
V
Chimpanzee
Pan troglodytes
XP_001150375
592
64537
S475
R
H
H
P
Q
V
L
S
M
K
F
K
T
G
V
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_545634
592
64708
S475
R
H
H
P
Q
V
L
S
M
K
F
K
T
G
V
Cat
Felis silvestris
Mouse
Mus musculus
Q9CWJ9
592
64199
S475
R
H
H
P
R
V
L
S
M
K
F
K
A
G
V
Rat
Rattus norvegicus
O35567
592
64190
S475
R
H
H
P
R
V
L
S
M
K
F
K
A
G
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
P31335
593
64396
S476
R
H
H
P
R
V
L
S
M
K
F
K
A
G
V
Frog
Xenopus laevis
NP_001090100
589
63809
G473
R
H
H
P
R
V
L
G
M
K
F
K
A
G
V
Zebra Danio
Brachydanio rerio
NP_001076265
590
64026
M474
H
H
P
G
V
L
S
M
R
F
R
S
G
V
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_651305
590
63305
G473
R
Q
H
P
S
V
A
G
M
K
F
K
A
G
V
Honey Bee
Apis mellifera
XP_395924
593
65708
I475
L
R
Q
H
P
K
V
I
N
M
K
F
K
K
N
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_793444
592
64337
S475
R
H
H
P
N
V
Q
S
M
K
F
K
P
G
V
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P38009
592
65245
E474
R
Q
H
P
R
V
L
E
I
K
W
A
K
G
V
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.8
N.A.
94.7
N.A.
91
91.2
N.A.
N.A.
83.4
77.5
79.3
N.A.
70.6
68.8
N.A.
68.7
Protein Similarity:
100
99.8
N.A.
98.1
N.A.
95.7
95.6
N.A.
N.A.
92.9
92.2
89.8
N.A.
83.2
81.4
N.A.
81.7
P-Site Identity:
100
100
N.A.
100
N.A.
86.6
86.6
N.A.
N.A.
86.6
80
6.6
N.A.
66.6
0
N.A.
80
P-Site Similarity:
100
100
N.A.
100
N.A.
93.3
93.3
N.A.
N.A.
93.3
86.6
13.3
N.A.
66.6
6.6
N.A.
80
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
61.8
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
76.8
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
53.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
73.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
9
0
0
0
0
9
42
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
9
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
9
75
9
0
0
0
% F
% Gly:
0
0
0
9
0
0
0
17
0
0
0
0
9
84
0
% G
% His:
9
75
84
9
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
9
9
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
9
0
0
0
84
9
75
17
9
9
% K
% Leu:
9
0
0
0
0
9
67
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
9
75
9
0
0
0
0
0
% M
% Asn:
0
0
0
0
9
0
0
0
9
0
0
0
0
0
9
% N
% Pro:
0
0
9
84
9
0
0
0
0
0
0
0
9
0
0
% P
% Gln:
0
17
9
0
25
0
9
0
0
0
0
0
0
0
0
% Q
% Arg:
84
9
0
0
42
0
0
0
9
0
9
0
0
0
0
% R
% Ser:
0
0
0
0
9
0
9
59
0
0
0
9
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
25
0
0
% T
% Val:
0
0
0
0
9
84
9
0
0
0
0
0
0
9
84
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
9
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _