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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PRKAR2B
All Species:
26.06
Human Site:
Y202
Identified Species:
38.22
UniProt:
P31323
Number Species:
15
Phosphosite Substitution
Charge Score:
0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P31323
NP_002727.2
418
46302
Y202
D
R
G
T
F
D
I
Y
V
K
C
D
G
V
G
Chimpanzee
Pan troglodytes
XP_001148361
477
52826
Y261
D
R
G
T
F
D
I
Y
V
K
C
D
G
V
G
Rhesus Macaque
Macaca mulatta
XP_001089109
461
51060
Y245
D
R
G
T
Y
D
I
Y
V
K
C
D
G
V
G
Dog
Lupus familis
XP_849179
417
46163
Y201
D
R
G
T
F
D
I
Y
V
K
C
D
G
V
G
Cat
Felis silvestris
Mouse
Mus musculus
P31324
416
46149
Y200
D
R
G
T
F
D
I
Y
V
K
C
D
G
V
G
Rat
Rattus norvegicus
P12369
416
46104
Y200
D
R
G
T
F
D
I
Y
V
K
C
D
G
V
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509189
323
36258
D121
G
R
C
V
G
N
Y
D
N
R
G
S
F
G
E
Chicken
Gallus gallus
Q5ZM91
382
43332
V177
D
E
G
D
N
F
Y
V
V
D
Q
G
E
M
D
Frog
Xenopus laevis
NP_001084637
402
45172
F186
D
R
G
T
Y
D
I
F
V
K
S
D
G
V
A
Zebra Danio
Brachydanio rerio
NP_001070838
397
44672
V184
E
R
G
V
Y
D
I
V
V
Q
K
D
G
V
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P81900
377
42730
V168
F
Y
V
I
E
S
G
V
Y
K
V
Y
I
N
D
Honey Bee
Apis mellifera
XP_392905
383
43849
V174
R
G
K
F
E
V
Y
V
R
D
Q
T
D
M
E
Nematode Worm
Caenorhab. elegans
P30625
366
41449
K164
D
N
F
Y
V
I
D
K
G
T
V
D
V
Y
V
Sea Urchin
Strong. purpuratus
Q26619
369
41770
E165
F
Y
V
I
D
R
G
E
Y
D
I
F
V
N
D
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P07278
416
47201
S204
I
N
C
L
E
E
K
S
V
P
K
G
A
T
I
Red Bread Mold
Neurospora crassa
Q01386
385
42138
Y178
E
K
G
R
F
E
V
Y
V
N
S
T
G
A
L
Conservation
Percent
Protein Identity:
100
86.5
90
96.6
N.A.
97.1
96.8
N.A.
70.3
34.6
78.4
68.1
N.A.
44
47.6
31.8
50.9
Protein Similarity:
100
87.2
90.2
98
N.A.
98
98.5
N.A.
74.1
52.3
85.4
80.6
N.A.
64.1
63.8
50.9
66.5
P-Site Identity:
100
100
93.3
100
N.A.
100
100
N.A.
6.6
20
73.3
60
N.A.
6.6
0
13.3
0
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
20
26.6
86.6
80
N.A.
6.6
6.6
13.3
0
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
33.9
36.8
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
51.9
51.4
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
33.3
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
13.3
60
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
0
7
7
7
% A
% Cys:
0
0
13
0
0
0
0
0
0
0
38
0
0
0
0
% C
% Asp:
57
0
0
7
7
50
7
7
0
19
0
57
7
0
19
% D
% Glu:
13
7
0
0
19
13
0
7
0
0
0
0
7
0
13
% E
% Phe:
13
0
7
7
38
7
0
7
0
0
0
7
7
0
0
% F
% Gly:
7
7
63
0
7
0
13
0
7
0
7
13
57
7
44
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
7
0
0
13
0
7
50
0
0
0
7
0
7
0
7
% I
% Lys:
0
7
7
0
0
0
7
7
0
50
13
0
0
0
0
% K
% Leu:
0
0
0
7
0
0
0
0
0
0
0
0
0
0
7
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
13
0
% M
% Asn:
0
13
0
0
7
7
0
0
7
7
0
0
0
13
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
7
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
7
13
0
0
0
0
% Q
% Arg:
7
57
0
7
0
7
0
0
7
7
0
0
0
0
0
% R
% Ser:
0
0
0
0
0
7
0
7
0
0
13
7
0
0
0
% S
% Thr:
0
0
0
44
0
0
0
0
0
7
0
13
0
7
0
% T
% Val:
0
0
13
13
7
7
7
25
69
0
13
0
13
50
7
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
13
0
7
19
0
19
44
13
0
0
7
0
7
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _