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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PRKAR2B
All Species:
26.67
Human Site:
S312
Identified Species:
39.11
UniProt:
P31323
Number Species:
15
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P31323
NP_002727.2
418
46302
S312
A
Q
G
D
S
A
D
S
F
F
I
V
E
S
G
Chimpanzee
Pan troglodytes
XP_001148361
477
52826
S371
A
Q
G
D
S
A
D
S
F
F
I
V
E
S
G
Rhesus Macaque
Macaca mulatta
XP_001089109
461
51060
S355
A
Q
G
D
S
A
D
S
F
F
I
V
E
S
G
Dog
Lupus familis
XP_849179
417
46163
S311
A
Q
G
D
S
A
D
S
F
F
I
V
E
S
G
Cat
Felis silvestris
Mouse
Mus musculus
P31324
416
46149
S310
A
Q
G
D
L
A
D
S
F
F
I
V
E
S
G
Rat
Rattus norvegicus
P12369
416
46104
S310
A
Q
G
D
S
A
D
S
F
F
I
V
E
S
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509189
323
36258
M230
S
G
E
V
K
I
T
M
K
R
K
N
K
Q
E
Chicken
Gallus gallus
Q5ZM91
382
43332
G287
G
Q
K
I
V
V
Q
G
E
P
G
D
E
F
F
Frog
Xenopus laevis
NP_001084637
402
45172
S296
A
Q
G
D
G
A
D
S
F
F
I
V
E
S
G
Zebra Danio
Brachydanio rerio
NP_001070838
397
44672
C294
M
Q
G
D
K
A
D
C
F
Y
I
V
E
S
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P81900
377
42730
G278
K
Q
G
D
A
A
D
G
M
Y
F
I
E
E
G
Honey Bee
Apis mellifera
XP_392905
383
43849
G284
K
Q
G
D
S
A
D
G
M
Y
F
V
E
D
G
Nematode Worm
Caenorhab. elegans
P30625
366
41449
P273
H
V
V
E
Q
G
Q
P
G
D
E
F
F
I
I
Sea Urchin
Strong. purpuratus
Q26619
369
41770
G275
A
Q
G
D
G
A
D
G
C
Y
F
I
E
A
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P07278
416
47201
A317
D
R
A
K
L
A
D
A
L
D
T
K
I
Y
Q
Red Bread Mold
Neurospora crassa
Q01386
385
42138
I288
K
Y
P
A
G
H
E
I
I
L
E
G
D
P
G
Conservation
Percent
Protein Identity:
100
86.5
90
96.6
N.A.
97.1
96.8
N.A.
70.3
34.6
78.4
68.1
N.A.
44
47.6
31.8
50.9
Protein Similarity:
100
87.2
90.2
98
N.A.
98
98.5
N.A.
74.1
52.3
85.4
80.6
N.A.
64.1
63.8
50.9
66.5
P-Site Identity:
100
100
100
100
N.A.
93.3
100
N.A.
0
13.3
93.3
73.3
N.A.
46.6
60
0
53.3
P-Site Similarity:
100
100
100
100
N.A.
93.3
100
N.A.
13.3
13.3
93.3
80
N.A.
66.6
66.6
6.6
73.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
33.9
36.8
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
51.9
51.4
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
13.3
6.6
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
26.6
20
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
50
0
7
7
7
75
0
7
0
0
0
0
0
7
0
% A
% Cys:
0
0
0
0
0
0
0
7
7
0
0
0
0
0
0
% C
% Asp:
7
0
0
69
0
0
75
0
0
13
0
7
7
7
0
% D
% Glu:
0
0
7
7
0
0
7
0
7
0
13
0
75
7
7
% E
% Phe:
0
0
0
0
0
0
0
0
50
44
19
7
7
7
7
% F
% Gly:
7
7
69
0
19
7
0
25
7
0
7
7
0
0
75
% G
% His:
7
0
0
0
0
7
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
7
0
7
0
7
7
0
50
13
7
7
7
% I
% Lys:
19
0
7
7
13
0
0
0
7
0
7
7
7
0
0
% K
% Leu:
0
0
0
0
13
0
0
0
7
7
0
0
0
0
0
% L
% Met:
7
0
0
0
0
0
0
7
13
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
7
0
0
0
% N
% Pro:
0
0
7
0
0
0
0
7
0
7
0
0
0
7
0
% P
% Gln:
0
75
0
0
7
0
13
0
0
0
0
0
0
7
7
% Q
% Arg:
0
7
0
0
0
0
0
0
0
7
0
0
0
0
0
% R
% Ser:
7
0
0
0
38
0
0
44
0
0
0
0
0
50
0
% S
% Thr:
0
0
0
0
0
0
7
0
0
0
7
0
0
0
0
% T
% Val:
0
7
7
7
7
7
0
0
0
0
0
57
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
7
0
0
0
0
0
0
0
25
0
0
0
7
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _