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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PRKAR1B
All Species:
24.55
Human Site:
S75
Identified Species:
38.57
UniProt:
P31321
Number Species:
14
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P31321
NP_002726.1
381
43073
S75
R
Q
K
S
N
S
Q
S
D
S
H
D
E
E
V
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001083834
375
41914
S75
R
Q
K
S
N
S
Q
S
D
S
H
D
E
E
V
Dog
Lupus familis
XP_537920
377
42817
S71
Q
I
Q
S
Q
Q
K
S
D
S
H
D
E
E
V
Cat
Felis silvestris
Mouse
Mus musculus
P12849
381
43206
C75
R
Q
K
S
N
S
Q
C
D
S
H
D
E
E
I
Rat
Rattus norvegicus
P81377
381
43264
C75
R
Q
K
S
N
S
Q
C
D
S
H
D
E
E
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509586
626
69567
S319
L
Q
K
A
S
S
R
S
D
S
R
E
D
E
I
Chicken
Gallus gallus
Q5ZM91
382
43332
S75
Q
Q
K
S
G
S
R
S
D
S
R
E
D
E
I
Frog
Xenopus laevis
NP_001085084
381
43157
S74
Q
Q
K
S
G
S
R
S
D
S
R
E
D
E
I
Zebra Danio
Brachydanio rerio
NP_001070091
380
42942
S74
R
Q
K
S
N
S
Q
S
D
S
H
D
D
E
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P16905
376
42221
V69
K
L
D
A
S
R
Q
V
I
S
P
D
D
C
E
Honey Bee
Apis mellifera
XP_396167
372
41646
A58
Q
K
L
E
R
E
Q
A
H
D
A
K
Q
Q
I
Nematode Worm
Caenorhab. elegans
P30625
366
41449
A57
E
K
L
N
E
Q
R
A
Q
E
G
G
N
P
D
Sea Urchin
Strong. purpuratus
Q26619
369
41770
A60
T
F
T
A
P
E
D
A
E
S
D
I
D
D
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P07278
416
47201
V85
Q
S
R
S
R
S
S
V
M
F
K
S
P
F
V
Red Bread Mold
Neurospora crassa
Q01386
385
42138
P79
R
R
Q
P
D
D
F
P
A
H
Y
N
L
G
R
Conservation
Percent
Protein Identity:
100
N.A.
72.9
93.9
N.A.
95
95
N.A.
52
82.9
83.1
92.9
N.A.
71.6
72.9
57.7
39.6
Protein Similarity:
100
N.A.
81
96.5
N.A.
98.6
98.6
N.A.
57.6
92.1
91
97.1
N.A.
84.2
84.7
73.2
56.4
P-Site Identity:
100
N.A.
100
60
N.A.
86.6
86.6
N.A.
46.6
53.3
53.3
93.3
N.A.
20
6.6
0
6.6
P-Site Similarity:
100
N.A.
100
80
N.A.
93.3
93.3
N.A.
86.6
86.6
86.6
100
N.A.
46.6
46.6
26.6
40
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
31.2
32.9
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
51.2
51.9
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
20
6.6
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
33.3
40
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
20
0
0
0
20
7
0
7
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
14
0
0
0
0
0
7
0
% C
% Asp:
0
0
7
0
7
7
7
0
60
7
7
47
40
7
7
% D
% Glu:
7
0
0
7
7
14
0
0
7
7
0
20
34
60
14
% E
% Phe:
0
7
0
0
0
0
7
0
0
7
0
0
0
7
0
% F
% Gly:
0
0
0
0
14
0
0
0
0
0
7
7
0
7
0
% G
% His:
0
0
0
0
0
0
0
0
7
7
40
0
0
0
0
% H
% Ile:
0
7
0
0
0
0
0
0
7
0
0
7
0
0
40
% I
% Lys:
7
14
54
0
0
0
7
0
0
0
7
7
0
0
0
% K
% Leu:
7
7
14
0
0
0
0
0
0
0
0
0
7
0
0
% L
% Met:
0
0
0
0
0
0
0
0
7
0
0
0
0
0
0
% M
% Asn:
0
0
0
7
34
0
0
0
0
0
0
7
7
0
0
% N
% Pro:
0
0
0
7
7
0
0
7
0
0
7
0
7
7
0
% P
% Gln:
34
54
14
0
7
14
47
0
7
0
0
0
7
7
0
% Q
% Arg:
40
7
7
0
14
7
27
0
0
0
20
0
0
0
7
% R
% Ser:
0
7
0
60
14
60
7
47
0
74
0
7
0
0
0
% S
% Thr:
7
0
7
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
14
0
0
0
0
0
0
34
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
7
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _