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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PRKAR1B
All Species:
48.48
Human Site:
S321
Identified Species:
76.19
UniProt:
P31321
Number Species:
14
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P31321
NP_002726.1
381
43073
S321
E
V
G
R
L
G
P
S
D
Y
F
G
E
I
A
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001083834
375
41914
S315
E
V
G
R
L
G
P
S
D
Y
F
G
E
I
A
Dog
Lupus familis
XP_537920
377
42817
S317
E
V
G
R
L
G
P
S
D
Y
F
G
E
I
A
Cat
Felis silvestris
Mouse
Mus musculus
P12849
381
43206
S321
E
V
G
R
L
G
P
S
D
Y
F
G
E
I
A
Rat
Rattus norvegicus
P81377
381
43264
S321
E
V
G
R
L
G
P
S
D
Y
F
G
E
I
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509586
626
69567
S566
E
V
G
R
L
G
P
S
D
Y
F
G
E
I
A
Chicken
Gallus gallus
Q5ZM91
382
43332
S322
E
V
G
R
L
A
P
S
D
Y
F
G
E
I
A
Frog
Xenopus laevis
NP_001085084
381
43157
S321
E
V
G
R
L
G
P
S
D
Y
F
G
E
I
A
Zebra Danio
Brachydanio rerio
NP_001070091
380
42942
S320
E
V
G
R
L
G
P
S
D
Y
F
G
E
I
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P16905
376
42221
S316
E
V
G
R
L
G
S
S
D
Y
F
G
E
I
A
Honey Bee
Apis mellifera
XP_396167
372
41646
S312
E
V
G
R
L
G
P
S
D
Y
F
G
E
I
A
Nematode Worm
Caenorhab. elegans
P30625
366
41449
S306
V
V
G
H
L
G
M
S
D
Y
F
G
E
I
A
Sea Urchin
Strong. purpuratus
Q26619
369
41770
G308
E
V
A
I
Y
N
Q
G
Q
Y
F
G
E
L
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P07278
416
47201
H363
V
I
N
K
L
K
D
H
D
Y
F
G
E
V
A
Red Bread Mold
Neurospora crassa
Q01386
385
42138
G323
P
V
K
N
Y
K
K
G
D
F
F
G
E
L
A
Conservation
Percent
Protein Identity:
100
N.A.
72.9
93.9
N.A.
95
95
N.A.
52
82.9
83.1
92.9
N.A.
71.6
72.9
57.7
39.6
Protein Similarity:
100
N.A.
81
96.5
N.A.
98.6
98.6
N.A.
57.6
92.1
91
97.1
N.A.
84.2
84.7
73.2
56.4
P-Site Identity:
100
N.A.
100
100
N.A.
100
100
N.A.
100
93.3
100
100
N.A.
93.3
100
80
46.6
P-Site Similarity:
100
N.A.
100
100
N.A.
100
100
N.A.
100
93.3
100
100
N.A.
93.3
100
80
53.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
31.2
32.9
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
51.2
51.9
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
46.6
40
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
66.6
53.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
7
0
0
7
0
0
0
0
0
0
0
0
100
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
7
0
94
0
0
0
0
0
0
% D
% Glu:
80
0
0
0
0
0
0
0
0
0
0
0
100
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
7
100
0
0
0
0
% F
% Gly:
0
0
80
0
0
74
0
14
0
0
0
100
0
0
0
% G
% His:
0
0
0
7
0
0
0
7
0
0
0
0
0
0
0
% H
% Ile:
0
7
0
7
0
0
0
0
0
0
0
0
0
80
0
% I
% Lys:
0
0
7
7
0
14
7
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
87
0
0
0
0
0
0
0
0
14
0
% L
% Met:
0
0
0
0
0
0
7
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
7
7
0
7
0
0
0
0
0
0
0
0
0
% N
% Pro:
7
0
0
0
0
0
67
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
7
0
7
0
0
0
0
0
0
% Q
% Arg:
0
0
0
74
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
0
0
0
7
80
0
0
0
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
14
94
0
0
0
0
0
0
0
0
0
0
0
7
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
14
0
0
0
0
94
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _