KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PRKAR1B
All Species:
39.39
Human Site:
S112
Identified Species:
61.9
UniProt:
P31321
Number Species:
14
Phosphosite Substitution
Charge Score:
0.21
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P31321
NP_002726.1
381
43073
S112
Y
T
E
E
D
A
V
S
Y
V
R
K
V
I
P
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001083834
375
41914
S112
Y
T
E
E
D
A
V
S
Y
V
R
K
V
I
P
Dog
Lupus familis
XP_537920
377
42817
S108
Y
T
E
E
D
A
V
S
Y
V
R
K
V
I
P
Cat
Felis silvestris
Mouse
Mus musculus
P12849
381
43206
S112
Y
T
E
E
D
A
V
S
Y
V
R
K
V
I
P
Rat
Rattus norvegicus
P81377
381
43264
S112
Y
T
E
E
D
A
V
S
Y
V
R
K
V
I
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509586
626
69567
S357
Y
T
E
E
D
A
A
S
Y
V
R
K
V
I
P
Chicken
Gallus gallus
Q5ZM91
382
43332
S113
Y
T
E
E
D
A
A
S
Y
V
R
K
V
I
P
Frog
Xenopus laevis
NP_001085084
381
43157
S112
Y
T
E
E
D
A
A
S
Y
V
R
K
V
I
P
Zebra Danio
Brachydanio rerio
NP_001070091
380
42942
S111
Y
T
E
E
D
A
V
S
Y
V
R
K
V
I
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P16905
376
42221
N107
V
T
E
E
D
A
T
N
Y
V
K
K
V
V
P
Honey Bee
Apis mellifera
XP_396167
372
41646
S103
V
S
E
E
D
A
T
S
Y
V
K
K
V
V
P
Nematode Worm
Caenorhab. elegans
P30625
366
41449
E97
P
I
K
E
D
D
T
E
Y
K
K
V
V
I
P
Sea Urchin
Strong. purpuratus
Q26619
369
41770
D96
P
E
A
D
N
D
T
D
T
Q
K
L
V
Y
P
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P07278
416
47201
W159
Q
P
N
N
F
D
D
W
T
P
D
H
Y
K
E
Red Bread Mold
Neurospora crassa
Q01386
385
42138
E118
P
K
T
A
E
Q
L
E
R
L
K
K
A
I
S
Conservation
Percent
Protein Identity:
100
N.A.
72.9
93.9
N.A.
95
95
N.A.
52
82.9
83.1
92.9
N.A.
71.6
72.9
57.7
39.6
Protein Similarity:
100
N.A.
81
96.5
N.A.
98.6
98.6
N.A.
57.6
92.1
91
97.1
N.A.
84.2
84.7
73.2
56.4
P-Site Identity:
100
N.A.
100
100
N.A.
100
100
N.A.
93.3
93.3
93.3
100
N.A.
66.6
66.6
40
13.3
P-Site Similarity:
100
N.A.
100
100
N.A.
100
100
N.A.
93.3
93.3
93.3
100
N.A.
86.6
86.6
53.3
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
31.2
32.9
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
51.2
51.9
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
0
13.3
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
0
40
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
7
7
0
74
20
0
0
0
0
0
7
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
7
80
20
7
7
0
0
7
0
0
0
0
% D
% Glu:
0
7
74
80
7
0
0
14
0
0
0
0
0
0
7
% E
% Phe:
0
0
0
0
7
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
7
0
0
0
% H
% Ile:
0
7
0
0
0
0
0
0
0
0
0
0
0
74
0
% I
% Lys:
0
7
7
0
0
0
0
0
0
7
34
80
0
7
0
% K
% Leu:
0
0
0
0
0
0
7
0
0
7
0
7
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
7
7
7
0
0
7
0
0
0
0
0
0
0
% N
% Pro:
20
7
0
0
0
0
0
0
0
7
0
0
0
0
87
% P
% Gln:
7
0
0
0
0
7
0
0
0
7
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
7
0
60
0
0
0
0
% R
% Ser:
0
7
0
0
0
0
0
67
0
0
0
0
0
0
7
% S
% Thr:
0
67
7
0
0
0
27
0
14
0
0
0
0
0
0
% T
% Val:
14
0
0
0
0
0
40
0
0
74
0
7
87
14
0
% V
% Trp:
0
0
0
0
0
0
0
7
0
0
0
0
0
0
0
% W
% Tyr:
60
0
0
0
0
0
0
0
80
0
0
0
7
7
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _