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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SDHA
All Species:
43.94
Human Site:
Y641
Identified Species:
80.56
UniProt:
P31040
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P31040
NP_004159.2
664
72692
Y641
T
G
K
V
T
L
E
Y
R
P
V
I
D
K
T
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
Q8K2B3
664
72567
Y641
T
G
K
V
T
L
E
Y
R
P
V
I
D
K
T
Rat
Rattus norvegicus
Q920L2
656
71597
Y633
T
G
K
V
T
L
D
Y
R
P
V
I
D
K
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513721
672
74157
Y649
T
G
K
V
T
L
E
Y
R
P
V
I
D
K
T
Chicken
Gallus gallus
Q9YHT1
665
72912
Y642
S
G
K
V
T
L
K
Y
R
P
V
I
D
R
T
Frog
Xenopus laevis
Q6PA58
665
72836
Y643
K
G
K
V
S
L
E
Y
R
P
V
I
D
T
T
Zebra Danio
Brachydanio rerio
Q7ZVF3
661
72059
Y638
T
G
K
V
T
L
E
Y
R
P
V
I
D
S
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q94523
661
72324
Y639
N
G
D
I
T
L
D
Y
R
N
V
I
D
T
T
Honey Bee
Apis mellifera
XP_623065
661
72444
F638
S
G
E
V
S
I
D
F
R
P
V
I
D
N
T
Nematode Worm
Caenorhab. elegans
Q09508
646
70380
Y623
T
G
E
V
S
L
D
Y
R
P
V
I
D
T
T
Sea Urchin
Strong. purpuratus
XP_801853
708
78118
Y685
T
G
E
V
K
L
E
Y
R
P
V
I
D
E
T
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
O82663
634
69638
Y612
D
E
K
V
R
L
D
Y
R
P
V
H
M
D
T
Baker's Yeast
Sacchar. cerevisiae
Q00711
640
70211
Y617
A
A
P
V
T
L
K
Y
R
R
V
I
D
H
T
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
N.A.
N.A.
N.A.
94.8
93.5
N.A.
90.1
88.7
86.4
82.9
N.A.
73.8
76
70.1
71.8
Protein Similarity:
100
N.A.
N.A.
N.A.
N.A.
96.9
96.5
N.A.
94
94.4
92.7
90.9
N.A.
84
85.5
80.5
82
P-Site Identity:
100
N.A.
N.A.
N.A.
N.A.
100
93.3
N.A.
100
80
80
86.6
N.A.
60
53.3
73.3
80
P-Site Similarity:
100
N.A.
N.A.
N.A.
N.A.
100
100
N.A.
100
100
86.6
93.3
N.A.
73.3
93.3
93.3
93.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
65.6
62.9
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
77.7
76.5
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
53.3
60
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
60
66.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
8
0
8
0
0
0
39
0
0
0
0
0
93
8
0
% D
% Glu:
0
8
24
0
0
0
47
0
0
0
0
0
0
8
0
% E
% Phe:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% F
% Gly:
0
85
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
8
0
8
0
% H
% Ile:
0
0
0
8
0
8
0
0
0
0
0
93
0
0
0
% I
% Lys:
8
0
62
0
8
0
16
0
0
0
0
0
0
31
0
% K
% Leu:
0
0
0
0
0
93
0
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% M
% Asn:
8
0
0
0
0
0
0
0
0
8
0
0
0
8
0
% N
% Pro:
0
0
8
0
0
0
0
0
0
85
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
8
0
0
0
100
8
0
0
0
8
0
% R
% Ser:
16
0
0
0
24
0
0
0
0
0
0
0
0
8
8
% S
% Thr:
54
0
0
0
62
0
0
0
0
0
0
0
0
24
93
% T
% Val:
0
0
0
93
0
0
0
0
0
0
100
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
93
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _