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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SDHA
All Species:
20
Human Site:
Y55
Identified Species:
36.67
UniProt:
P31040
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P31040
NP_004159.2
664
72692
Y55
S
D
S
I
S
A
Q
Y
P
V
V
D
H
E
F
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
Q8K2B3
664
72567
Y55
S
D
A
I
S
T
Q
Y
P
V
V
D
H
E
F
Rat
Rattus norvegicus
Q920L2
656
71597
D55
P
V
V
D
H
E
F
D
A
V
V
V
G
A
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513721
672
74157
Y63
S
D
S
I
S
T
Q
Y
P
V
V
D
H
E
Y
Chicken
Gallus gallus
Q9YHT1
665
72912
Y56
S
D
S
I
S
T
Q
Y
P
V
V
D
H
E
F
Frog
Xenopus laevis
Q6PA58
665
72836
Y58
S
D
S
I
S
T
Q
Y
P
V
V
D
H
E
F
Zebra Danio
Brachydanio rerio
Q7ZVF3
661
72059
D60
P
V
V
D
H
E
F
D
A
V
V
V
G
A
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q94523
661
72324
A61
V
V
D
H
A
Y
D
A
I
V
V
G
A
G
G
Honey Bee
Apis mellifera
XP_623065
661
72444
V55
V
S
K
H
Y
P
L
V
D
H
T
Y
D
A
V
Nematode Worm
Caenorhab. elegans
Q09508
646
70380
R56
G
A
G
G
A
G
L
R
A
A
M
G
L
A
E
Sea Urchin
Strong. purpuratus
XP_801853
708
78118
Y98
T
S
Q
V
S
R
D
Y
P
V
V
D
H
T
F
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
O82663
634
69638
A60
V
V
V
G
A
G
G
A
G
L
R
A
A
I
G
Baker's Yeast
Sacchar. cerevisiae
Q00711
640
70211
V56
I
D
H
E
Y
D
C
V
V
I
G
A
G
G
A
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
N.A.
N.A.
N.A.
94.8
93.5
N.A.
90.1
88.7
86.4
82.9
N.A.
73.8
76
70.1
71.8
Protein Similarity:
100
N.A.
N.A.
N.A.
N.A.
96.9
96.5
N.A.
94
94.4
92.7
90.9
N.A.
84
85.5
80.5
82
P-Site Identity:
100
N.A.
N.A.
N.A.
N.A.
86.6
13.3
N.A.
86.6
93.3
93.3
13.3
N.A.
13.3
0
0
53.3
P-Site Similarity:
100
N.A.
N.A.
N.A.
N.A.
93.3
13.3
N.A.
93.3
93.3
93.3
13.3
N.A.
20
0
13.3
66.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
65.6
62.9
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
77.7
76.5
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
13.3
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
8
0
24
8
0
16
24
8
0
16
16
31
8
% A
% Cys:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
0
% C
% Asp:
0
47
8
16
0
8
16
16
8
0
0
47
8
0
0
% D
% Glu:
0
0
0
8
0
16
0
0
0
0
0
0
0
39
8
% E
% Phe:
0
0
0
0
0
0
16
0
0
0
0
0
0
0
39
% F
% Gly:
8
0
8
16
0
16
8
0
8
0
8
16
24
16
31
% G
% His:
0
0
8
16
16
0
0
0
0
8
0
0
47
0
0
% H
% Ile:
8
0
0
39
0
0
0
0
8
8
0
0
0
8
0
% I
% Lys:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
0
0
16
0
0
8
0
0
8
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
16
0
0
0
0
8
0
0
47
0
0
0
0
0
0
% P
% Gln:
0
0
8
0
0
0
39
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
8
0
8
0
0
8
0
0
0
0
% R
% Ser:
39
16
31
0
47
0
0
0
0
0
0
0
0
0
0
% S
% Thr:
8
0
0
0
0
31
0
0
0
0
8
0
0
8
0
% T
% Val:
24
31
24
8
0
0
0
16
8
70
70
16
0
0
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
16
8
0
47
0
0
0
8
0
0
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _