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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SDHA
All Species:
40.3
Human Site:
Y365
Identified Species:
73.89
UniProt:
P31040
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P31040
NP_004159.2
664
72692
Y365
G
P
E
K
D
H
V
Y
L
Q
L
H
H
L
P
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
Q8K2B3
664
72567
Y365
G
P
E
K
D
H
V
Y
L
Q
L
H
H
L
P
Rat
Rattus norvegicus
Q920L2
656
71597
Y357
G
P
E
K
D
H
V
Y
L
Q
L
H
H
L
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513721
672
74157
Y373
G
P
E
K
D
H
V
Y
L
Q
L
H
H
L
P
Chicken
Gallus gallus
Q9YHT1
665
72912
Y366
G
P
E
K
D
H
V
Y
L
Q
L
H
H
L
P
Frog
Xenopus laevis
Q6PA58
665
72836
Y368
G
K
D
K
D
H
V
Y
L
Q
L
H
H
L
P
Zebra Danio
Brachydanio rerio
Q7ZVF3
661
72059
H362
G
P
D
K
D
H
V
H
L
Q
L
H
H
L
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q94523
661
72324
Y362
G
P
E
K
D
H
V
Y
L
Q
L
H
H
L
P
Honey Bee
Apis mellifera
XP_623065
661
72444
Y362
G
P
E
K
D
H
I
Y
L
Q
L
H
H
L
P
Nematode Worm
Caenorhab. elegans
Q09508
646
70380
Y346
G
P
D
K
D
H
I
Y
L
Q
L
H
H
L
P
Sea Urchin
Strong. purpuratus
XP_801853
708
78118
Y408
G
P
D
K
D
H
V
Y
L
Q
L
S
H
L
P
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
O82663
634
69638
G345
M
E
I
R
E
G
R
G
V
G
P
H
K
D
H
Baker's Yeast
Sacchar. cerevisiae
Q00711
640
70211
K352
G
R
G
V
G
K
K
K
D
H
M
Y
L
Q
L
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
N.A.
N.A.
N.A.
94.8
93.5
N.A.
90.1
88.7
86.4
82.9
N.A.
73.8
76
70.1
71.8
Protein Similarity:
100
N.A.
N.A.
N.A.
N.A.
96.9
96.5
N.A.
94
94.4
92.7
90.9
N.A.
84
85.5
80.5
82
P-Site Identity:
100
N.A.
N.A.
N.A.
N.A.
100
100
N.A.
100
100
86.6
86.6
N.A.
100
93.3
86.6
86.6
P-Site Similarity:
100
N.A.
N.A.
N.A.
N.A.
100
100
N.A.
100
100
93.3
100
N.A.
100
100
100
93.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
65.6
62.9
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
77.7
76.5
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
26.6
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
31
0
85
0
0
0
8
0
0
0
0
8
0
% D
% Glu:
0
8
54
0
8
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
93
0
8
0
8
8
0
8
0
8
0
0
0
0
0
% G
% His:
0
0
0
0
0
85
0
8
0
8
0
85
85
0
8
% H
% Ile:
0
0
8
0
0
0
16
0
0
0
0
0
0
0
0
% I
% Lys:
0
8
0
85
0
8
8
8
0
0
0
0
8
0
0
% K
% Leu:
0
0
0
0
0
0
0
0
85
0
85
0
8
85
8
% L
% Met:
8
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
77
0
0
0
0
0
0
0
0
8
0
0
0
85
% P
% Gln:
0
0
0
0
0
0
0
0
0
85
0
0
0
8
0
% Q
% Arg:
0
8
0
8
0
0
8
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
8
0
0
70
0
8
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
77
0
0
0
8
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _