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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SDHA
All Species:
37.27
Human Site:
T638
Identified Species:
68.33
UniProt:
P31040
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P31040
NP_004159.2
664
72692
T638
D
V
G
T
G
K
V
T
L
E
Y
R
P
V
I
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
Q8K2B3
664
72567
T638
D
I
K
T
G
K
V
T
L
E
Y
R
P
V
I
Rat
Rattus norvegicus
Q920L2
656
71597
T630
D
T
K
T
G
K
V
T
L
D
Y
R
P
V
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513721
672
74157
T646
D
T
K
T
G
K
V
T
L
E
Y
R
P
V
I
Chicken
Gallus gallus
Q9YHT1
665
72912
T639
D
V
K
S
G
K
V
T
L
K
Y
R
P
V
I
Frog
Xenopus laevis
Q6PA58
665
72836
S640
V
D
K
K
G
K
V
S
L
E
Y
R
P
V
I
Zebra Danio
Brachydanio rerio
Q7ZVF3
661
72059
T635
D
P
E
T
G
K
V
T
L
E
Y
R
P
V
I
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q94523
661
72324
T636
C
N
D
N
G
D
I
T
L
D
Y
R
N
V
I
Honey Bee
Apis mellifera
XP_623065
661
72444
S635
N
V
R
S
G
E
V
S
I
D
F
R
P
V
I
Nematode Worm
Caenorhab. elegans
Q09508
646
70380
S620
N
I
E
T
G
E
V
S
L
D
Y
R
P
V
I
Sea Urchin
Strong. purpuratus
XP_801853
708
78118
K682
D
E
H
T
G
E
V
K
L
E
Y
R
P
V
I
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
O82663
634
69638
R609
Y
W
E
D
E
K
V
R
L
D
Y
R
P
V
H
Baker's Yeast
Sacchar. cerevisiae
Q00711
640
70211
T614
K
D
V
A
A
P
V
T
L
K
Y
R
R
V
I
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
N.A.
N.A.
N.A.
94.8
93.5
N.A.
90.1
88.7
86.4
82.9
N.A.
73.8
76
70.1
71.8
Protein Similarity:
100
N.A.
N.A.
N.A.
N.A.
96.9
96.5
N.A.
94
94.4
92.7
90.9
N.A.
84
85.5
80.5
82
P-Site Identity:
100
N.A.
N.A.
N.A.
N.A.
86.6
80
N.A.
86.6
80
66.6
86.6
N.A.
46.6
46.6
60
73.3
P-Site Similarity:
100
N.A.
N.A.
N.A.
N.A.
93.3
86.6
N.A.
86.6
93.3
73.3
86.6
N.A.
60
93.3
93.3
80
Percent
Protein Identity:
N.A.
N.A.
N.A.
65.6
62.9
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
77.7
76.5
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
46.6
46.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
53.3
53.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
8
8
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
54
16
8
8
0
8
0
0
0
39
0
0
0
0
0
% D
% Glu:
0
8
24
0
8
24
0
0
0
47
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% F
% Gly:
0
0
8
0
85
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
8
% H
% Ile:
0
16
0
0
0
0
8
0
8
0
0
0
0
0
93
% I
% Lys:
8
0
39
8
0
62
0
8
0
16
0
0
0
0
0
% K
% Leu:
0
0
0
0
0
0
0
0
93
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
16
8
0
8
0
0
0
0
0
0
0
0
8
0
0
% N
% Pro:
0
8
0
0
0
8
0
0
0
0
0
0
85
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
8
0
0
0
0
8
0
0
0
100
8
0
0
% R
% Ser:
0
0
0
16
0
0
0
24
0
0
0
0
0
0
0
% S
% Thr:
0
16
0
54
0
0
0
62
0
0
0
0
0
0
0
% T
% Val:
8
24
8
0
0
0
93
0
0
0
0
0
0
100
0
% V
% Trp:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
8
0
0
0
0
0
0
0
0
0
93
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _