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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SDHA All Species: 24.24
Human Site: T551 Identified Species: 44.44
UniProt: P31040 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P31040 NP_004159.2 664 72692 T551 G D L K H L K T F D R G M V W
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta
Dog Lupus familis
Cat Felis silvestris
Mouse Mus musculus Q8K2B3 664 72567 T551 G D L K H L K T F D R G M V W
Rat Rattus norvegicus Q920L2 656 71597 T543 G D L Q H L K T F D R G M V W
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001513721 672 74157 T559 G D L K N L K T F D R G M V W
Chicken Gallus gallus Q9YHT1 665 72912 T552 C D L A H L K T F D R G I V W
Frog Xenopus laevis Q6PA58 665 72836 T554 S S M D D I K T F D R G I V W
Zebra Danio Brachydanio rerio Q7ZVF3 661 72059 T548 K S M D D I K T F D R G I V W
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q94523 661 72324 V549 K Q F K D I K V V D R S L I W
Honey Bee Apis mellifera XP_623065 661 72444 V548 K K L N D L K V L D K S M I W
Nematode Worm Caenorhab. elegans Q09508 646 70380 V533 K D Q A H L N V A D K G L V W
Sea Urchin Strong. purpuratus XP_801853 708 78118 L595 K N L D N I K L F D R G I V W
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana O82663 634 69638 E524 R T Q E T L E E G C Q L I D K
Baker's Yeast Sacchar. cerevisiae Q00711 640 70211 N531 S L D E G V R N I T A V E K T
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. N.A. N.A. N.A. 94.8 93.5 N.A. 90.1 88.7 86.4 82.9 N.A. 73.8 76 70.1 71.8
Protein Similarity: 100 N.A. N.A. N.A. N.A. 96.9 96.5 N.A. 94 94.4 92.7 90.9 N.A. 84 85.5 80.5 82
P-Site Identity: 100 N.A. N.A. N.A. N.A. 100 93.3 N.A. 93.3 80 53.3 53.3 N.A. 33.3 40 46.6 53.3
P-Site Similarity: 100 N.A. N.A. N.A. N.A. 100 100 N.A. 100 86.6 73.3 73.3 N.A. 53.3 53.3 60 80
Percent
Protein Identity: N.A. N.A. N.A. 65.6 62.9 N.A.
Protein Similarity: N.A. N.A. N.A. 77.7 76.5 N.A.
P-Site Identity: N.A. N.A. N.A. 6.6 0 N.A.
P-Site Similarity: N.A. N.A. N.A. 33.3 20 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 16 0 0 0 0 8 0 8 0 0 0 0 % A
% Cys: 8 0 0 0 0 0 0 0 0 8 0 0 0 0 0 % C
% Asp: 0 47 8 24 31 0 0 0 0 85 0 0 0 8 0 % D
% Glu: 0 0 0 16 0 0 8 8 0 0 0 0 8 0 0 % E
% Phe: 0 0 8 0 0 0 0 0 62 0 0 0 0 0 0 % F
% Gly: 31 0 0 0 8 0 0 0 8 0 0 70 0 0 0 % G
% His: 0 0 0 0 39 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 31 0 0 8 0 0 0 39 16 0 % I
% Lys: 39 8 0 31 0 0 77 0 0 0 16 0 0 8 8 % K
% Leu: 0 8 54 0 0 62 0 8 8 0 0 8 16 0 0 % L
% Met: 0 0 16 0 0 0 0 0 0 0 0 0 39 0 0 % M
% Asn: 0 8 0 8 16 0 8 8 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 8 16 8 0 0 0 0 0 0 8 0 0 0 0 % Q
% Arg: 8 0 0 0 0 0 8 0 0 0 70 0 0 0 0 % R
% Ser: 16 16 0 0 0 0 0 0 0 0 0 16 0 0 0 % S
% Thr: 0 8 0 0 8 0 0 54 0 8 0 0 0 0 8 % T
% Val: 0 0 0 0 0 8 0 24 8 0 0 8 0 70 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 85 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _