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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SDHA
All Species:
11.21
Human Site:
S8
Identified Species:
20.56
UniProt:
P31040
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P31040
NP_004159.2
664
72692
S8
M
S
G
V
R
G
L
S
R
L
L
S
A
R
R
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
Q8K2B3
664
72567
S8
M
A
G
V
G
A
V
S
R
L
L
R
G
R
R
Rat
Rattus norvegicus
Q920L2
656
71597
S8
M
A
G
V
G
A
V
S
R
L
L
R
G
R
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513721
672
74157
V16
K
C
D
G
F
H
L
V
F
P
F
S
Y
C
D
Chicken
Gallus gallus
Q9YHT1
665
72912
R9
A
A
V
V
A
A
S
R
S
L
A
K
C
W
L
Frog
Xenopus laevis
Q6PA58
665
72836
L11
L
K
V
A
P
S
R
L
L
S
R
A
L
Q
L
Zebra Danio
Brachydanio rerio
Q7ZVF3
661
72059
T13
A
A
S
R
V
L
G
T
K
I
L
S
C
K
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q94523
661
72324
N14
V
P
S
I
L
A
K
N
A
V
A
S
M
Q
R
Honey Bee
Apis mellifera
XP_623065
661
72444
S8
M
S
G
L
L
K
L
S
S
L
L
V
R
N
P
Nematode Worm
Caenorhab. elegans
Q09508
646
70380
L9
L
R
A
A
S
N
G
L
R
N
T
V
A
A
R
Sea Urchin
Strong. purpuratus
XP_801853
708
78118
P51
L
L
R
G
Q
V
S
P
E
A
A
N
M
E
F
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
O82663
634
69638
A13
S
R
G
F
R
A
P
A
S
K
T
S
S
L
F
Baker's Yeast
Sacchar. cerevisiae
Q00711
640
70211
L9
L
S
L
K
K
S
A
L
S
K
L
T
L
L
R
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
N.A.
N.A.
N.A.
94.8
93.5
N.A.
90.1
88.7
86.4
82.9
N.A.
73.8
76
70.1
71.8
Protein Similarity:
100
N.A.
N.A.
N.A.
N.A.
96.9
96.5
N.A.
94
94.4
92.7
90.9
N.A.
84
85.5
80.5
82
P-Site Identity:
100
N.A.
N.A.
N.A.
N.A.
60
60
N.A.
13.3
13.3
0
13.3
N.A.
13.3
46.6
20
0
P-Site Similarity:
100
N.A.
N.A.
N.A.
N.A.
73.3
73.3
N.A.
13.3
20
20
46.6
N.A.
46.6
53.3
26.6
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
65.6
62.9
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
77.7
76.5
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
20
20
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
33.3
40
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
16
31
8
16
8
39
8
8
8
8
24
8
16
8
0
% A
% Cys:
0
8
0
0
0
0
0
0
0
0
0
0
16
8
0
% C
% Asp:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
8
% D
% Glu:
0
0
0
0
0
0
0
0
8
0
0
0
0
8
0
% E
% Phe:
0
0
0
8
8
0
0
0
8
0
8
0
0
0
16
% F
% Gly:
0
0
39
16
16
8
16
0
0
0
0
0
16
0
0
% G
% His:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
8
0
0
0
0
0
8
0
0
0
0
0
% I
% Lys:
8
8
0
8
8
8
8
0
8
16
0
8
0
8
0
% K
% Leu:
31
8
8
8
16
8
24
24
8
39
47
0
16
16
16
% L
% Met:
31
0
0
0
0
0
0
0
0
0
0
0
16
0
0
% M
% Asn:
0
0
0
0
0
8
0
8
0
8
0
8
0
8
0
% N
% Pro:
0
8
0
0
8
0
8
8
0
8
0
0
0
0
8
% P
% Gln:
0
0
0
0
8
0
0
0
0
0
0
0
0
16
0
% Q
% Arg:
0
16
8
8
16
0
8
8
31
0
8
16
8
24
47
% R
% Ser:
8
24
16
0
8
16
16
31
31
8
0
39
8
0
8
% S
% Thr:
0
0
0
0
0
0
0
8
0
0
16
8
0
0
0
% T
% Val:
8
0
16
31
8
8
16
8
0
8
0
16
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _