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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SDHA
All Species:
35.76
Human Site:
S470
Identified Species:
65.56
UniProt:
P31040
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P31040
NP_004159.2
664
72692
S470
F
G
R
A
C
A
L
S
I
E
E
S
C
R
P
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
Q8K2B3
664
72567
S470
F
G
R
A
C
A
L
S
I
A
E
S
C
R
P
Rat
Rattus norvegicus
Q920L2
656
71597
S462
F
G
R
A
C
A
L
S
I
A
E
S
C
R
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513721
672
74157
S478
F
G
R
A
C
A
L
S
I
A
E
S
C
R
P
Chicken
Gallus gallus
Q9YHT1
665
72912
T471
F
G
R
A
C
A
L
T
I
A
E
T
C
K
P
Frog
Xenopus laevis
Q6PA58
665
72836
S473
F
G
R
A
C
A
L
S
I
A
E
S
C
K
P
Zebra Danio
Brachydanio rerio
Q7ZVF3
661
72059
T467
F
G
R
A
C
A
L
T
I
A
E
I
D
T
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q94523
661
72324
T468
F
G
R
A
C
A
K
T
I
A
E
L
N
K
P
Honey Bee
Apis mellifera
XP_623065
661
72444
T467
F
G
R
A
C
A
K
T
I
A
A
E
N
K
P
Nematode Worm
Caenorhab. elegans
Q09508
646
70380
D452
F
G
R
A
C
A
I
D
I
L
K
N
T
S
A
Sea Urchin
Strong. purpuratus
XP_801853
708
78118
T514
F
G
R
A
C
A
H
T
I
T
E
E
N
R
P
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
O82663
634
69638
S446
A
N
R
L
G
A
N
S
L
L
D
I
V
V
F
Baker's Yeast
Sacchar. cerevisiae
Q00711
640
70211
L453
G
A
N
S
L
L
D
L
V
V
F
G
R
A
V
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
N.A.
N.A.
N.A.
94.8
93.5
N.A.
90.1
88.7
86.4
82.9
N.A.
73.8
76
70.1
71.8
Protein Similarity:
100
N.A.
N.A.
N.A.
N.A.
96.9
96.5
N.A.
94
94.4
92.7
90.9
N.A.
84
85.5
80.5
82
P-Site Identity:
100
N.A.
N.A.
N.A.
N.A.
93.3
93.3
N.A.
93.3
73.3
86.6
66.6
N.A.
60
53.3
46.6
66.6
P-Site Similarity:
100
N.A.
N.A.
N.A.
N.A.
93.3
93.3
N.A.
93.3
93.3
93.3
73.3
N.A.
73.3
66.6
66.6
73.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
65.6
62.9
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
77.7
76.5
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
20
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
33.3
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
8
0
85
0
93
0
0
0
62
8
0
0
8
8
% A
% Cys:
0
0
0
0
85
0
0
0
0
0
0
0
47
0
0
% C
% Asp:
0
0
0
0
0
0
8
8
0
0
8
0
8
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
8
70
16
0
0
0
% E
% Phe:
85
0
0
0
0
0
0
0
0
0
8
0
0
0
8
% F
% Gly:
8
85
0
0
8
0
0
0
0
0
0
8
0
0
0
% G
% His:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
8
0
85
0
0
16
0
0
0
% I
% Lys:
0
0
0
0
0
0
16
0
0
0
8
0
0
31
0
% K
% Leu:
0
0
0
8
8
8
54
8
8
16
0
8
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
8
8
0
0
0
8
0
0
0
0
8
24
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
77
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
93
0
0
0
0
0
0
0
0
0
8
39
0
% R
% Ser:
0
0
0
8
0
0
0
47
0
0
0
39
0
8
0
% S
% Thr:
0
0
0
0
0
0
0
39
0
8
0
8
8
8
0
% T
% Val:
0
0
0
0
0
0
0
0
8
8
0
0
8
8
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _