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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SDHA
All Species:
45.76
Human Site:
S346
Identified Species:
83.89
UniProt:
P31040
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P31040
NP_004159.2
664
72692
S346
S
R
D
V
V
S
R
S
M
T
L
E
I
R
E
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
Q8K2B3
664
72567
S346
S
R
D
V
V
S
R
S
M
T
L
E
I
R
E
Rat
Rattus norvegicus
Q920L2
656
71597
S338
S
R
D
V
V
S
R
S
M
T
L
E
I
R
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513721
672
74157
S354
S
R
D
V
V
S
R
S
M
T
I
E
I
R
E
Chicken
Gallus gallus
Q9YHT1
665
72912
S347
S
R
D
V
V
S
R
S
M
T
I
E
I
R
E
Frog
Xenopus laevis
Q6PA58
665
72836
S349
S
R
D
V
V
S
R
S
M
T
I
E
I
R
E
Zebra Danio
Brachydanio rerio
Q7ZVF3
661
72059
S343
S
R
D
V
V
S
R
S
M
T
I
E
I
R
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q94523
661
72324
S343
S
R
D
V
V
S
R
S
M
T
I
E
I
M
E
Honey Bee
Apis mellifera
XP_623065
661
72444
S343
S
R
D
V
V
S
R
S
M
T
I
E
I
R
E
Nematode Worm
Caenorhab. elegans
Q09508
646
70380
S327
S
R
D
V
V
S
R
S
M
T
V
E
I
M
E
Sea Urchin
Strong. purpuratus
XP_801853
708
78118
S389
S
R
D
V
V
S
R
S
M
T
I
E
I
R
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
O82663
634
69638
D325
R
Y
A
P
T
A
K
D
L
A
S
R
D
V
V
Baker's Yeast
Sacchar. cerevisiae
Q00711
640
70211
S335
L
A
C
R
D
V
V
S
R
A
I
T
M
E
I
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
N.A.
N.A.
N.A.
94.8
93.5
N.A.
90.1
88.7
86.4
82.9
N.A.
73.8
76
70.1
71.8
Protein Similarity:
100
N.A.
N.A.
N.A.
N.A.
96.9
96.5
N.A.
94
94.4
92.7
90.9
N.A.
84
85.5
80.5
82
P-Site Identity:
100
N.A.
N.A.
N.A.
N.A.
100
100
N.A.
93.3
93.3
93.3
93.3
N.A.
86.6
93.3
86.6
93.3
P-Site Similarity:
100
N.A.
N.A.
N.A.
N.A.
100
100
N.A.
100
100
100
100
N.A.
93.3
100
93.3
100
Percent
Protein Identity:
N.A.
N.A.
N.A.
65.6
62.9
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
77.7
76.5
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
20
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
8
0
0
8
0
0
0
16
0
0
0
0
0
% A
% Cys:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
85
0
8
0
0
8
0
0
0
0
8
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
85
0
8
85
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
62
0
85
0
8
% I
% Lys:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
0
% K
% Leu:
8
0
0
0
0
0
0
0
8
0
24
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
85
0
0
0
8
16
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
8
85
0
8
0
0
85
0
8
0
0
8
0
70
0
% R
% Ser:
85
0
0
0
0
85
0
93
0
0
8
0
0
0
0
% S
% Thr:
0
0
0
0
8
0
0
0
0
85
0
8
0
0
0
% T
% Val:
0
0
0
85
85
8
8
0
0
0
8
0
0
8
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _