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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HTR1F
All Species:
21.52
Human Site:
Y245
Identified Species:
43.03
UniProt:
P30939
Number Species:
11
Phosphosite Substitution
Charge Score:
0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P30939
NP_000857.1
366
41709
Y245
T
K
S
V
S
T
S
Y
V
L
E
K
S
L
S
Chimpanzee
Pan troglodytes
Q9N2D9
365
41472
Y245
T
K
S
V
S
T
S
Y
V
L
E
K
S
L
S
Rhesus Macaque
Macaca mulatta
XP_001081998
366
41701
Y245
A
K
S
V
S
T
P
Y
A
P
E
K
T
L
T
Dog
Lupus familis
XP_539028
365
41558
D246
T
Q
T
F
C
V
S
D
F
S
T
S
D
P
T
Cat
Felis silvestris
Mouse
Mus musculus
Q02284
366
41959
Y245
I
K
L
V
S
T
S
Y
M
L
E
K
S
L
S
Rat
Rattus norvegicus
P30940
366
41862
Y245
I
K
L
V
S
T
S
Y
M
L
E
K
S
L
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515164
368
42187
Y245
A
R
L
V
S
T
Q
Y
M
P
E
K
S
L
S
Chicken
Gallus gallus
XP_425535
366
41839
T245
K
L
T
S
M
P
S
T
I
E
K
T
S
D
P
Frog
Xenopus laevis
Q98998
408
45769
Q252
K
E
K
Q
R
G
A
Q
Q
E
L
E
E
V
G
Zebra Danio
Brachydanio rerio
Q90WY6
432
49119
N257
R
E
D
S
R
R
E
N
G
H
C
S
S
S
P
Tiger Blowfish
Takifugu rubipres
O42385
423
46982
A267
H
K
R
A
N
G
D
A
V
S
A
E
W
K
R
Fruit Fly
Dros. melanogaster
P20905
564
60843
T384
Q
A
P
P
L
G
H
T
E
L
A
S
S
G
N
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.4
97.2
56
N.A.
94.2
92.3
N.A.
88.3
82.5
40.2
34.7
40.1
28
N.A.
N.A.
N.A.
Protein Similarity:
100
99.4
98.6
72.6
N.A.
97.5
96.1
N.A.
95.1
91.2
59
53.4
57.4
40.4
N.A.
N.A.
N.A.
P-Site Identity:
100
100
60
13.3
N.A.
80
80
N.A.
60
13.3
0
6.6
13.3
13.3
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
73.3
33.3
N.A.
86.6
86.6
N.A.
73.3
33.3
26.6
13.3
26.6
20
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
17
9
0
9
0
0
9
9
9
0
17
0
0
0
0
% A
% Cys:
0
0
0
0
9
0
0
0
0
0
9
0
0
0
0
% C
% Asp:
0
0
9
0
0
0
9
9
0
0
0
0
9
9
0
% D
% Glu:
0
17
0
0
0
0
9
0
9
17
50
17
9
0
0
% E
% Phe:
0
0
0
9
0
0
0
0
9
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
25
0
0
9
0
0
0
0
9
9
% G
% His:
9
0
0
0
0
0
9
0
0
9
0
0
0
0
0
% H
% Ile:
17
0
0
0
0
0
0
0
9
0
0
0
0
0
0
% I
% Lys:
17
50
9
0
0
0
0
0
0
0
9
50
0
9
0
% K
% Leu:
0
9
25
0
9
0
0
0
0
42
9
0
0
50
0
% L
% Met:
0
0
0
0
9
0
0
0
25
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
9
0
0
9
0
0
0
0
0
0
9
% N
% Pro:
0
0
9
9
0
9
9
0
0
17
0
0
0
9
17
% P
% Gln:
9
9
0
9
0
0
9
9
9
0
0
0
0
0
0
% Q
% Arg:
9
9
9
0
17
9
0
0
0
0
0
0
0
0
9
% R
% Ser:
0
0
25
17
50
0
50
0
0
17
0
25
67
9
42
% S
% Thr:
25
0
17
0
0
50
0
17
0
0
9
9
9
0
17
% T
% Val:
0
0
0
50
0
9
0
0
25
0
0
0
0
9
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
9
0
0
% W
% Tyr:
0
0
0
0
0
0
0
50
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _