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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: HTR1F All Species: 15.45
Human Site: S244 Identified Species: 30.91
UniProt: P30939 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0.18
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P30939 NP_000857.1 366 41709 S244 S T K S V S T S Y V L E K S L
Chimpanzee Pan troglodytes Q9N2D9 365 41472 S244 S T K S V S T S Y V L E K S L
Rhesus Macaque Macaca mulatta XP_001081998 366 41701 P244 S A K S V S T P Y A P E K T L
Dog Lupus familis XP_539028 365 41558 S245 L T Q T F C V S D F S T S D P
Cat Felis silvestris
Mouse Mus musculus Q02284 366 41959 S244 S I K L V S T S Y M L E K S L
Rat Rattus norvegicus P30940 366 41862 S244 S I K L V S T S Y M L E K S L
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001515164 368 42187 Q244 N A R L V S T Q Y M P E K S L
Chicken Gallus gallus XP_425535 366 41839 S244 T K L T S M P S T I E K T S D
Frog Xenopus laevis Q98998 408 45769 A251 P K E K Q R G A Q Q E L E E V
Zebra Danio Brachydanio rerio Q90WY6 432 49119 E256 S R E D S R R E N G H C S S S
Tiger Blowfish Takifugu rubipres O42385 423 46982 D266 F H K R A N G D A V S A E W K
Fruit Fly Dros. melanogaster P20905 564 60843 H383 P Q A P P L G H T E L A S S G
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.4 97.2 56 N.A. 94.2 92.3 N.A. 88.3 82.5 40.2 34.7 40.1 28 N.A. N.A. N.A.
Protein Similarity: 100 99.4 98.6 72.6 N.A. 97.5 96.1 N.A. 95.1 91.2 59 53.4 57.4 40.4 N.A. N.A. N.A.
P-Site Identity: 100 100 66.6 13.3 N.A. 80 80 N.A. 53.3 13.3 0 13.3 13.3 13.3 N.A. N.A. N.A.
P-Site Similarity: 100 100 73.3 26.6 N.A. 86.6 86.6 N.A. 73.3 40 26.6 20 26.6 13.3 N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 17 9 0 9 0 0 9 9 9 0 17 0 0 0 % A
% Cys: 0 0 0 0 0 9 0 0 0 0 0 9 0 0 0 % C
% Asp: 0 0 0 9 0 0 0 9 9 0 0 0 0 9 9 % D
% Glu: 0 0 17 0 0 0 0 9 0 9 17 50 17 9 0 % E
% Phe: 9 0 0 0 9 0 0 0 0 9 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 25 0 0 9 0 0 0 0 9 % G
% His: 0 9 0 0 0 0 0 9 0 0 9 0 0 0 0 % H
% Ile: 0 17 0 0 0 0 0 0 0 9 0 0 0 0 0 % I
% Lys: 0 17 50 9 0 0 0 0 0 0 0 9 50 0 9 % K
% Leu: 9 0 9 25 0 9 0 0 0 0 42 9 0 0 50 % L
% Met: 0 0 0 0 0 9 0 0 0 25 0 0 0 0 0 % M
% Asn: 9 0 0 0 0 9 0 0 9 0 0 0 0 0 0 % N
% Pro: 17 0 0 9 9 0 9 9 0 0 17 0 0 0 9 % P
% Gln: 0 9 9 0 9 0 0 9 9 9 0 0 0 0 0 % Q
% Arg: 0 9 9 9 0 17 9 0 0 0 0 0 0 0 0 % R
% Ser: 50 0 0 25 17 50 0 50 0 0 17 0 25 67 9 % S
% Thr: 9 25 0 17 0 0 50 0 17 0 0 9 9 9 0 % T
% Val: 0 0 0 0 50 0 9 0 0 25 0 0 0 0 9 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 9 0 % W
% Tyr: 0 0 0 0 0 0 0 0 50 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _