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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CHRNB4
All Species:
3.64
Human Site:
S354
Identified Species:
7.27
UniProt:
P30926
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P30926
NP_000741.1
498
56380
S354
M
K
R
P
G
P
D
S
S
P
A
R
A
F
P
Chimpanzee
Pan troglodytes
Q5IS76
494
56903
W357
P
Q
V
L
L
M
R
W
P
L
D
K
T
R
G
Rhesus Macaque
Macaca mulatta
XP_001107489
376
42290
S239
K
R
P
G
P
D
S
S
L
A
R
A
F
L
P
Dog
Lupus familis
XP_852548
481
54099
R343
P
T
F
L
F
M
K
R
P
D
S
S
P
S
R
Cat
Felis silvestris
Mouse
Mus musculus
Q8R493
495
55791
V353
M
K
R
P
G
L
E
V
S
P
A
R
V
P
H
Rat
Rattus norvegicus
P12392
495
55843
V353
M
K
R
P
G
L
E
V
S
L
V
R
V
P
H
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513131
979
112159
P353
M
N
R
P
E
N
H
P
A
R
Q
R
P
G
P
Chicken
Gallus gallus
P26153
470
53767
N332
L
F
M
K
R
P
E
N
N
S
P
R
Q
K
P
Frog
Xenopus laevis
NP_001088299
499
57252
C355
M
K
Q
P
R
Q
N
C
A
R
Q
R
L
R
Q
Zebra Danio
Brachydanio rerio
XP_696993
525
59084
S364
M
Q
R
P
R
G
H
S
A
R
Q
R
L
R
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P25162
519
60122
L367
M
R
R
T
Q
Y
T
L
P
D
Y
D
D
S
T
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q9N587
502
57373
T352
N
V
H
Y
R
S
P
T
T
H
T
M
P
K
W
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
42.9
72.4
81.9
N.A.
82.9
81.9
N.A.
38.2
73
62.1
62.8
N.A.
42.9
N.A.
42.8
N.A.
Protein Similarity:
100
61.2
73
87.9
N.A.
89.3
88.7
N.A.
44.5
80.3
75.1
74.2
N.A.
61.4
N.A.
63.7
N.A.
P-Site Identity:
100
0
13.3
0
N.A.
60
46.6
N.A.
33.3
20
26.6
33.3
N.A.
13.3
N.A.
0
N.A.
P-Site Similarity:
100
13.3
20
6.6
N.A.
66.6
53.3
N.A.
40
46.6
46.6
46.6
N.A.
20
N.A.
13.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
25
9
17
9
9
0
0
% A
% Cys:
0
0
0
0
0
0
0
9
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
9
9
0
0
17
9
9
9
0
0
% D
% Glu:
0
0
0
0
9
0
25
0
0
0
0
0
0
0
0
% E
% Phe:
0
9
9
0
9
0
0
0
0
0
0
0
9
9
0
% F
% Gly:
0
0
0
9
25
9
0
0
0
0
0
0
0
9
9
% G
% His:
0
0
9
0
0
0
17
0
0
9
0
0
0
0
17
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
9
34
0
9
0
0
9
0
0
0
0
9
0
17
0
% K
% Leu:
9
0
0
17
9
17
0
9
9
17
0
0
17
9
0
% L
% Met:
59
0
9
0
0
17
0
0
0
0
0
9
0
0
0
% M
% Asn:
9
9
0
0
0
9
9
9
9
0
0
0
0
0
0
% N
% Pro:
17
0
9
50
9
17
9
9
25
17
9
0
25
17
34
% P
% Gln:
0
17
9
0
9
9
0
0
0
0
25
0
9
0
17
% Q
% Arg:
0
17
50
0
34
0
9
9
0
25
9
59
0
25
9
% R
% Ser:
0
0
0
0
0
9
9
25
25
9
9
9
0
17
0
% S
% Thr:
0
9
0
9
0
0
9
9
9
0
9
0
9
0
9
% T
% Val:
0
9
9
0
0
0
0
17
0
0
9
0
17
0
0
% V
% Trp:
0
0
0
0
0
0
0
9
0
0
0
0
0
0
9
% W
% Tyr:
0
0
0
9
0
9
0
0
0
0
9
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _