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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CHRNB4
All Species:
20.61
Human Site:
S218
Identified Species:
41.21
UniProt:
P30926
Number Species:
11
Phosphosite Substitution
Charge Score:
0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P30926
NP_000741.1
498
56380
S218
T
V
N
P
Q
D
P
S
Y
V
D
V
T
Y
D
Chimpanzee
Pan troglodytes
Q5IS76
494
56903
N221
Y
K
H
D
I
K
Y
N
C
C
E
E
I
Y
T
Rhesus Macaque
Macaca mulatta
XP_001107489
376
42290
Y103
V
N
P
Q
D
P
S
Y
V
D
V
T
Y
D
F
Dog
Lupus familis
XP_852548
481
54099
N207
L
P
G
R
R
T
V
N
P
Q
D
P
S
Y
V
Cat
Felis silvestris
Mouse
Mus musculus
Q8R493
495
55791
S217
T
V
N
P
Q
D
P
S
Y
V
D
V
T
Y
D
Rat
Rattus norvegicus
P12392
495
55843
S217
T
V
N
P
Q
D
P
S
Y
V
D
V
T
Y
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513131
979
112159
S217
T
I
N
P
L
D
P
S
Y
V
D
V
T
Y
D
Chicken
Gallus gallus
P26153
470
53767
D196
R
R
T
E
N
P
L
D
P
N
Y
V
D
V
T
Frog
Xenopus laevis
NP_001088299
499
57252
T219
N
E
N
P
N
D
S
T
Y
V
D
I
T
Y
D
Zebra Danio
Brachydanio rerio
XP_696993
525
59084
T228
T
V
S
P
L
D
A
T
Y
V
D
L
T
Y
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P25162
519
60122
P231
Y
Y
P
D
T
L
E
P
F
S
D
I
T
F
K
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q9N587
502
57373
L216
V
V
D
R
G
I
D
L
S
D
Y
Y
P
S
V
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
42.9
72.4
81.9
N.A.
82.9
81.9
N.A.
38.2
73
62.1
62.8
N.A.
42.9
N.A.
42.8
N.A.
Protein Similarity:
100
61.2
73
87.9
N.A.
89.3
88.7
N.A.
44.5
80.3
75.1
74.2
N.A.
61.4
N.A.
63.7
N.A.
P-Site Identity:
100
6.6
0
13.3
N.A.
100
100
N.A.
86.6
6.6
60
66.6
N.A.
13.3
N.A.
6.6
N.A.
P-Site Similarity:
100
26.6
0
33.3
N.A.
100
100
N.A.
93.3
6.6
73.3
86.6
N.A.
33.3
N.A.
13.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
9
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
9
9
0
0
0
0
0
% C
% Asp:
0
0
9
17
9
50
9
9
0
17
67
0
9
9
50
% D
% Glu:
0
9
0
9
0
0
9
0
0
0
9
9
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
9
0
0
0
0
9
9
% F
% Gly:
0
0
9
0
9
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
9
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
9
0
0
9
9
0
0
0
0
0
17
9
0
0
% I
% Lys:
0
9
0
0
0
9
0
0
0
0
0
0
0
0
9
% K
% Leu:
9
0
0
0
17
9
9
9
0
0
0
9
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
9
9
42
0
17
0
0
17
0
9
0
0
0
0
0
% N
% Pro:
0
9
17
50
0
17
34
9
17
0
0
9
9
0
0
% P
% Gln:
0
0
0
9
25
0
0
0
0
9
0
0
0
0
0
% Q
% Arg:
9
9
0
17
9
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
9
0
0
0
17
34
9
9
0
0
9
9
0
% S
% Thr:
42
0
9
0
9
9
0
17
0
0
0
9
59
0
17
% T
% Val:
17
42
0
0
0
0
9
0
9
50
9
42
0
9
17
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
17
9
0
0
0
0
9
9
50
0
17
9
9
67
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _