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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PRDX6
All Species:
30.39
Human Site:
Y220
Identified Species:
44.57
UniProt:
P30041
Number Species:
15
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P30041
NP_004896.1
224
25035
Y220
S
G
K
K
Y
L
R
Y
T
P
Q
P
_
_
_
Chimpanzee
Pan troglodytes
XP_001148286
209
23201
L201
Q
W
R
D
L
G
P
L
Q
P
L
P
P
G
F
Rhesus Macaque
Macaca mulatta
XP_001101473
224
25004
Y220
S
G
K
K
Y
L
R
Y
T
P
Q
P
_
_
_
Dog
Lupus familis
XP_537190
245
27431
Y241
S
G
K
K
Y
L
R
Y
T
P
Q
P
_
_
_
Cat
Felis silvestris
Mouse
Mus musculus
O08709
224
24852
Y220
S
G
K
K
Y
L
R
Y
T
P
Q
P
_
_
_
Rat
Rattus norvegicus
O35244
224
24800
Y220
S
G
K
K
Y
L
R
Y
T
P
Q
P
_
_
_
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515331
223
24797
Y219
S
A
K
R
Y
L
R
Y
T
P
Q
P
_
_
_
Chicken
Gallus gallus
Q5ZJF4
224
24958
Y219
S
G
K
K
Y
L
R
Y
T
P
Q
P
E
_
_
Frog
Xenopus laevis
NP_001082669
224
25051
Y219
S
G
K
K
Y
L
R
Y
T
A
Q
P
Q
_
_
Zebra Danio
Brachydanio rerio
NP_957099
222
24990
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_523463
222
24827
I218
S
G
K
S
Y
L
R
I
T
P
Q
P
_
_
_
Honey Bee
Apis mellifera
XP_395319
220
24904
I215
S
G
K
S
Y
V
R
I
V
S
Q
P
L
_
_
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_784500
189
21008
L185
S
G
K
G
Y
I
R
L
T
P
Q
P
_
_
_
Poplar Tree
Populus trichocarpa
Maize
Zea mays
A2SZW8
229
24887
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
O04005
216
24063
H212
S
K
K
G
Y
L
R
H
T
E
V
S
_
_
_
Baker's Yeast
Sacchar. cerevisiae
P34227
261
29477
F257
E
I
K
P
Y
L
R
F
T
K
S
K
_
_
_
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
84.3
98.6
84.9
N.A.
89.7
91.5
N.A.
85.2
86.1
80.3
73.6
N.A.
60.2
59.3
N.A.
58
Protein Similarity:
100
87.5
99.5
89.3
N.A.
93.7
95
N.A.
91.5
93.7
87.5
86.1
N.A.
70
72.7
N.A.
63.8
P-Site Identity:
100
13.3
100
100
N.A.
100
100
N.A.
83.3
92.3
84.6
0
N.A.
83.3
53.8
N.A.
75
P-Site Similarity:
100
26.6
100
100
N.A.
100
100
N.A.
91.6
92.3
84.6
0
N.A.
83.3
61.5
N.A.
83.3
Percent
Protein Identity:
N.A.
51.5
N.A.
50.4
42.5
N.A.
Protein Similarity:
N.A.
67.6
N.A.
66.5
56.3
N.A.
P-Site Identity:
N.A.
0
N.A.
50
41.6
N.A.
P-Site Similarity:
N.A.
0
N.A.
58.3
50
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
7
0
0
0
0
0
0
0
7
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
7
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
7
0
0
0
0
0
0
0
0
7
0
0
7
0
0
% E
% Phe:
0
0
0
0
0
0
0
7
0
0
0
0
0
0
7
% F
% Gly:
0
63
0
13
0
7
0
0
0
0
0
0
0
7
0
% G
% His:
0
0
0
0
0
0
0
7
0
0
0
0
0
0
0
% H
% Ile:
0
7
0
0
0
7
0
13
0
0
0
0
0
0
0
% I
% Lys:
0
7
82
44
0
0
0
0
0
7
0
7
0
0
0
% K
% Leu:
0
0
0
0
7
69
0
13
0
0
7
0
7
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
7
0
0
7
0
0
63
0
75
7
0
0
% P
% Gln:
7
0
0
0
0
0
0
0
7
0
69
0
7
0
0
% Q
% Arg:
0
0
7
7
0
0
82
0
0
0
0
0
0
0
0
% R
% Ser:
75
0
0
13
0
0
0
0
0
7
7
7
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
75
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
7
0
0
7
0
7
0
0
0
0
% V
% Trp:
0
7
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
82
0
0
50
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
63
82
82
% _