KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PRDX6
All Species:
27.27
Human Site:
S186
Identified Species:
40
UniProt:
P30041
Number Species:
15
Phosphosite Substitution
Charge Score:
0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P30041
NP_004896.1
224
25035
S186
V
D
W
K
D
G
D
S
V
M
V
L
P
T
I
Chimpanzee
Pan troglodytes
XP_001148286
209
23201
S166
E
I
L
R
V
V
I
S
L
Q
L
T
A
E
K
Rhesus Macaque
Macaca mulatta
XP_001101473
224
25004
S186
V
D
W
K
D
G
D
S
V
M
V
L
P
T
I
Dog
Lupus familis
XP_537190
245
27431
S207
V
D
W
K
D
G
D
S
V
M
V
L
P
T
I
Cat
Felis silvestris
Mouse
Mus musculus
O08709
224
24852
S186
V
D
W
K
K
G
E
S
V
M
V
V
P
T
L
Rat
Rattus norvegicus
O35244
224
24800
S186
V
D
W
K
K
G
E
S
V
M
V
L
P
T
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515331
223
24797
S185
V
D
W
K
S
G
D
S
V
M
V
I
P
S
L
Chicken
Gallus gallus
Q5ZJF4
224
24958
S185
V
D
W
K
C
G
D
S
V
M
V
V
P
T
L
Frog
Xenopus laevis
NP_001082669
224
25051
R185
V
D
W
K
P
G
D
R
V
M
V
P
P
N
V
Zebra Danio
Brachydanio rerio
NP_957099
222
24990
E185
V
D
W
K
P
G
Q
E
V
M
V
I
P
S
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_523463
222
24827
K184
A
D
W
K
Q
G
G
K
C
M
V
L
P
T
V
Honey Bee
Apis mellifera
XP_395319
220
24904
E182
V
D
W
K
I
G
E
E
V
M
I
Q
P
I
V
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_784500
189
21008
D152
A
D
W
K
S
G
E
D
C
M
V
L
P
N
I
Poplar Tree
Populus trichocarpa
Maize
Zea mays
A2SZW8
229
24887
G190
T
P
A
N
W
K
P
G
E
C
A
V
I
A
P
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
O04005
216
24063
D176
T
P
V
N
W
K
P
D
Q
P
V
V
I
S
P
Baker's Yeast
Sacchar. cerevisiae
P34227
261
29477
Q211
L
R
V
I
D
A
L
Q
L
T
D
K
E
G
V
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
84.3
98.6
84.9
N.A.
89.7
91.5
N.A.
85.2
86.1
80.3
73.6
N.A.
60.2
59.3
N.A.
58
Protein Similarity:
100
87.5
99.5
89.3
N.A.
93.7
95
N.A.
91.5
93.7
87.5
86.1
N.A.
70
72.7
N.A.
63.8
P-Site Identity:
100
6.6
100
100
N.A.
73.3
80
N.A.
73.3
80
66.6
60
N.A.
60
53.3
N.A.
60
P-Site Similarity:
100
26.6
100
100
N.A.
93.3
93.3
N.A.
93.3
93.3
73.3
80
N.A.
66.6
73.3
N.A.
66.6
Percent
Protein Identity:
N.A.
51.5
N.A.
50.4
42.5
N.A.
Protein Similarity:
N.A.
67.6
N.A.
66.5
56.3
N.A.
P-Site Identity:
N.A.
0
N.A.
6.6
6.6
N.A.
P-Site Similarity:
N.A.
6.6
N.A.
20
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
13
0
7
0
0
7
0
0
0
0
7
0
7
7
0
% A
% Cys:
0
0
0
0
7
0
0
0
13
7
0
0
0
0
0
% C
% Asp:
0
75
0
0
25
0
38
13
0
0
7
0
0
0
0
% D
% Glu:
7
0
0
0
0
0
25
13
7
0
0
0
7
7
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
75
7
7
0
0
0
0
0
7
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
7
0
7
7
0
7
0
0
0
7
13
13
7
25
% I
% Lys:
0
0
0
75
13
13
0
7
0
0
0
7
0
0
7
% K
% Leu:
7
0
7
0
0
0
7
0
13
0
7
38
0
0
32
% L
% Met:
0
0
0
0
0
0
0
0
0
75
0
0
0
0
0
% M
% Asn:
0
0
0
13
0
0
0
0
0
0
0
0
0
13
0
% N
% Pro:
0
13
0
0
13
0
13
0
0
7
0
7
75
0
13
% P
% Gln:
0
0
0
0
7
0
7
7
7
7
0
7
0
0
0
% Q
% Arg:
0
7
0
7
0
0
0
7
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
0
13
0
0
50
0
0
0
0
0
19
0
% S
% Thr:
13
0
0
0
0
0
0
0
0
7
0
7
0
44
0
% T
% Val:
63
0
13
0
7
7
0
0
63
0
75
25
0
0
25
% V
% Trp:
0
0
75
0
13
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _