KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PDHA2
All Species:
8.48
Human Site:
S372
Identified Species:
14.36
UniProt:
P29803
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P29803
NP_005381.1
388
42933
S372
H
I
Y
S
S
D
S
S
F
E
V
R
G
A
N
Chimpanzee
Pan troglodytes
A5A6L0
390
43219
P374
H
I
Y
S
S
D
P
P
F
E
V
R
G
A
N
Rhesus Macaque
Macaca mulatta
XP_001097880
420
46631
S404
H
I
Y
S
S
D
S
S
F
E
V
R
G
A
N
Dog
Lupus familis
XP_537975
390
43375
P374
H
I
Y
S
S
D
P
P
F
E
V
R
G
A
N
Cat
Felis silvestris
Mouse
Mus musculus
P35486
390
43213
P374
H
I
Y
S
S
D
P
P
F
E
V
R
G
A
N
Rat
Rattus norvegicus
P26284
390
43208
P374
H
I
Y
S
S
D
P
P
F
E
V
R
G
A
N
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514100
568
62886
P552
H
I
Y
S
R
E
P
P
F
E
V
R
G
P
N
Chicken
Gallus gallus
NP_001012562
399
44424
P381
H
I
Y
F
N
E
P
P
F
E
V
R
G
P
N
Frog
Xenopus laevis
NP_001087610
400
44764
T384
H
I
Y
R
N
D
P
T
F
D
V
R
G
A
N
Zebra Danio
Brachydanio rerio
NP_001002399
393
43605
P377
H
I
F
Y
N
D
A
P
L
E
V
R
G
T
N
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P52899
397
43773
A368
D
I
Y
H
N
T
P
A
Q
E
I
R
G
A
T
Sea Urchin
Strong. purpuratus
XP_001175746
386
42313
A368
E
T
F
T
N
I
Y
A
N
T
A
P
M
R
V
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P52901
389
43041
G373
N
V
Y
V
K
G
F
G
T
E
S
F
G
P
D
Baker's Yeast
Sacchar. cerevisiae
P16387
420
46325
L400
K
G
T
E
T
P
T
L
R
G
R
I
P
E
D
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
84.6
88.3
84.8
N.A.
85.3
84.8
N.A.
56.6
76.4
74.7
73.2
N.A.
N.A.
N.A.
56.4
56.9
Protein Similarity:
100
90.7
90.7
91.2
N.A.
91
90.7
N.A.
62.5
85.7
86.7
87.2
N.A.
N.A.
N.A.
70
71.9
P-Site Identity:
100
86.6
100
86.6
N.A.
86.6
86.6
N.A.
66.6
60
66.6
53.3
N.A.
N.A.
N.A.
40
0
P-Site Similarity:
100
86.6
100
86.6
N.A.
86.6
86.6
N.A.
73.3
73.3
86.6
73.3
N.A.
N.A.
N.A.
60
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
49.8
46.9
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
65.3
62.3
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
20
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
40
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
8
15
0
0
8
0
0
58
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
8
0
0
0
0
58
0
0
0
8
0
0
0
0
15
% D
% Glu:
8
0
0
8
0
15
0
0
0
79
0
0
0
8
0
% E
% Phe:
0
0
15
8
0
0
8
0
65
0
0
8
0
0
0
% F
% Gly:
0
8
0
0
0
8
0
8
0
8
0
0
86
0
0
% G
% His:
72
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
79
0
0
0
8
0
0
0
0
8
8
0
0
0
% I
% Lys:
8
0
0
0
8
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
0
0
0
8
8
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% M
% Asn:
8
0
0
0
36
0
0
0
8
0
0
0
0
0
72
% N
% Pro:
0
0
0
0
0
8
58
50
0
0
0
8
8
22
0
% P
% Gln:
0
0
0
0
0
0
0
0
8
0
0
0
0
0
0
% Q
% Arg:
0
0
0
8
8
0
0
0
8
0
8
79
0
8
0
% R
% Ser:
0
0
0
50
43
0
15
15
0
0
8
0
0
0
0
% S
% Thr:
0
8
8
8
8
8
8
8
8
8
0
0
0
8
8
% T
% Val:
0
8
0
8
0
0
0
0
0
0
72
0
0
0
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
79
8
0
0
8
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _