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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: GTF2E1 All Species: 22.73
Human Site: S334 Identified Species: 45.45
UniProt: P29083 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P29083 NP_005504.2 439 49452 S334 I H E K K T S S A M A G S V G
Chimpanzee Pan troglodytes XP_001165043 439 49464 S334 I H E K K T S S A M A G S V G
Rhesus Macaque Macaca mulatta XP_001111102 439 49497 S334 I H E K K T S S A M A G S V G
Dog Lupus familis XP_545124 438 49371 S333 I H E K K T P S A T A G S V G
Cat Felis silvestris
Mouse Mus musculus Q9D0D5 440 49575 S334 I H E K K T S S V T A G S V G
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001509961 297 33458 P222 K Q R W V V G P A A G T V S A
Chicken Gallus gallus XP_416551 441 49929 S335 I H E K K T P S A S T V T V G
Frog Xenopus laevis NP_001080455 433 49015 V329 I H E K K S A V P V G A S S A
Zebra Danio Brachydanio rerio NP_001038610 447 50244 A333 I H E K R S G A G P G G S A V
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_524026 429 48267 Q333 Q H E K Q P G Q K E P H M K G
Honey Bee Apis mellifera XP_395253 419 47339 T330 A H E K K G G T N S A A A I K
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_790549 436 49593 H322 I M K A L L A H E R K V G Q R
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99 98.4 96.1 N.A. 92.7 N.A. N.A. 55.3 81.1 76 71.8 N.A. 44.1 43.5 N.A. 40.7
Protein Similarity: 100 99.5 98.4 97.2 N.A. 95 N.A. N.A. 59.6 89.1 85.8 83 N.A. 63 62.4 N.A. 61
P-Site Identity: 100 100 100 86.6 N.A. 86.6 N.A. N.A. 6.6 66.6 40 40 N.A. 26.6 33.3 N.A. 6.6
P-Site Similarity: 100 100 100 86.6 N.A. 86.6 N.A. N.A. 6.6 73.3 60 60 N.A. 33.3 53.3 N.A. 20
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 9 0 0 9 0 0 17 9 50 9 50 17 9 9 17 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 84 0 0 0 0 0 9 9 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 9 34 0 9 0 25 50 9 0 59 % G
% His: 0 84 0 0 0 0 0 9 0 0 0 9 0 0 0 % H
% Ile: 75 0 0 0 0 0 0 0 0 0 0 0 0 9 0 % I
% Lys: 9 0 9 84 67 0 0 0 9 0 9 0 0 9 9 % K
% Leu: 0 0 0 0 9 9 0 0 0 0 0 0 0 0 0 % L
% Met: 0 9 0 0 0 0 0 0 0 25 0 0 9 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 9 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 9 17 9 9 9 9 0 0 0 0 % P
% Gln: 9 9 0 0 9 0 0 9 0 0 0 0 0 9 0 % Q
% Arg: 0 0 9 0 9 0 0 0 0 9 0 0 0 0 9 % R
% Ser: 0 0 0 0 0 17 34 50 0 17 0 0 59 17 0 % S
% Thr: 0 0 0 0 0 50 0 9 0 17 9 9 9 0 0 % T
% Val: 0 0 0 0 9 9 0 9 9 9 0 17 9 50 9 % V
% Trp: 0 0 0 9 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _