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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
GTF2E1
All Species:
21.52
Human Site:
S284
Identified Species:
43.03
UniProt:
P29083
Number Species:
11
Phosphosite Substitution
Charge Score:
0.18
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P29083
NP_005504.2
439
49452
S284
R
P
I
W
L
R
E
S
T
V
Q
G
A
Y
G
Chimpanzee
Pan troglodytes
XP_001165043
439
49464
S284
R
P
I
W
L
R
E
S
T
V
Q
G
A
Y
G
Rhesus Macaque
Macaca mulatta
XP_001111102
439
49497
S284
R
P
I
W
L
R
E
S
T
V
Q
G
A
Y
S
Dog
Lupus familis
XP_545124
438
49371
S283
R
P
I
W
L
R
E
S
T
V
Q
G
A
Y
S
Cat
Felis silvestris
Mouse
Mus musculus
Q9D0D5
440
49575
S284
R
P
I
W
L
R
E
S
T
V
Q
G
A
Y
S
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509961
297
33458
V197
L
L
R
E
T
E
D
V
N
L
A
Y
E
I
L
Chicken
Gallus gallus
XP_416551
441
49929
S285
R
P
I
W
L
R
E
S
T
V
Q
G
A
Y
D
Frog
Xenopus laevis
NP_001080455
433
49015
E302
D
D
T
D
P
F
Q
E
R
E
E
S
R
P
M
Zebra Danio
Brachydanio rerio
NP_001038610
447
50244
G306
D
S
V
V
T
Q
E
G
I
T
G
R
G
A
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_524026
429
48267
A306
A
A
D
A
V
Q
T
A
S
G
S
G
H
R
N
Honey Bee
Apis mellifera
XP_395253
419
47339
N294
D
G
V
N
T
Q
E
N
I
L
D
K
A
A
A
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_790549
436
49593
E296
A
P
S
G
S
G
V
E
T
M
E
A
E
R
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99
98.4
96.1
N.A.
92.7
N.A.
N.A.
55.3
81.1
76
71.8
N.A.
44.1
43.5
N.A.
40.7
Protein Similarity:
100
99.5
98.4
97.2
N.A.
95
N.A.
N.A.
59.6
89.1
85.8
83
N.A.
63
62.4
N.A.
61
P-Site Identity:
100
100
93.3
93.3
N.A.
93.3
N.A.
N.A.
0
93.3
0
6.6
N.A.
6.6
13.3
N.A.
13.3
P-Site Similarity:
100
100
93.3
93.3
N.A.
93.3
N.A.
N.A.
13.3
93.3
13.3
20
N.A.
33.3
40
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
17
9
0
9
0
0
0
9
0
0
9
9
59
17
25
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
25
9
9
9
0
0
9
0
0
0
9
0
0
0
9
% D
% Glu:
0
0
0
9
0
9
67
17
0
9
17
0
17
0
0
% E
% Phe:
0
0
0
0
0
9
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
9
0
9
0
9
0
9
0
9
9
59
9
0
17
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
9
0
0
% H
% Ile:
0
0
50
0
0
0
0
0
17
0
0
0
0
9
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
9
0
0
0
% K
% Leu:
9
9
0
0
50
0
0
0
0
17
0
0
0
0
9
% L
% Met:
0
0
0
0
0
0
0
0
0
9
0
0
0
0
9
% M
% Asn:
0
0
0
9
0
0
0
9
9
0
0
0
0
0
9
% N
% Pro:
0
59
0
0
9
0
0
0
0
0
0
0
0
9
0
% P
% Gln:
0
0
0
0
0
25
9
0
0
0
50
0
0
0
0
% Q
% Arg:
50
0
9
0
0
50
0
0
9
0
0
9
9
17
0
% R
% Ser:
0
9
9
0
9
0
0
50
9
0
9
9
0
0
25
% S
% Thr:
0
0
9
0
25
0
9
0
59
9
0
0
0
0
0
% T
% Val:
0
0
17
9
9
0
9
9
0
50
0
0
0
0
0
% V
% Trp:
0
0
0
50
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
9
0
50
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _