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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
POLD1
All Species:
34.55
Human Site:
Y739
Identified Species:
63.33
UniProt:
P28340
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P28340
NP_002682.2
1107
123631
Y739
K
Q
L
V
E
S
K
Y
T
V
E
N
G
Y
S
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001116065
1327
147636
Y739
K
Q
L
V
E
S
K
Y
T
V
E
N
G
Y
S
Dog
Lupus familis
XP_851285
1107
123714
Y739
K
Q
L
V
E
S
K
Y
T
V
E
N
G
Y
S
Cat
Felis silvestris
Mouse
Mus musculus
P52431
1105
123765
Y737
K
Q
L
V
E
S
K
Y
T
V
E
N
G
Y
D
Rat
Rattus norvegicus
O54747
1103
123583
Y735
K
Q
L
V
E
T
K
Y
T
L
E
N
G
Y
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001087694
1109
125430
Y744
K
Q
L
V
E
S
K
Y
T
L
D
N
G
Y
K
Zebra Danio
Brachydanio rerio
NP_001034899
1105
124931
Y743
K
Q
L
V
E
S
R
Y
T
L
D
N
G
Y
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P54358
1092
124887
Y728
K
N
E
V
E
S
H
Y
T
Q
A
N
G
Y
E
Honey Bee
Apis mellifera
XP_623795
1105
126747
Y741
K
Q
E
V
E
E
Q
Y
C
I
S
K
G
Y
K
Nematode Worm
Caenorhab. elegans
P90829
1081
120811
G710
V
E
R
I
Y
K
K
G
A
L
D
G
K
C
P
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
XP_002307042
1081
121993
F721
K
K
L
V
E
D
K
F
T
I
L
G
G
Y
E
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9LVN7
1081
121718
F735
K
K
L
V
E
D
K
F
T
T
L
G
G
Y
Q
Baker's Yeast
Sacchar. cerevisiae
P15436
1097
124572
Y746
K
T
A
V
Q
E
K
Y
C
I
K
N
G
Y
K
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
80.6
94.1
N.A.
89.4
89.8
N.A.
N.A.
N.A.
70.9
69.7
N.A.
59.4
58.9
49.6
N.A.
Protein Similarity:
100
N.A.
81.5
96.4
N.A.
94.1
94.3
N.A.
N.A.
N.A.
84
83
N.A.
74.8
74.4
67.9
N.A.
P-Site Identity:
100
N.A.
100
100
N.A.
93.3
80
N.A.
N.A.
N.A.
80
73.3
N.A.
60
46.6
6.6
N.A.
P-Site Similarity:
100
N.A.
100
100
N.A.
93.3
93.3
N.A.
N.A.
N.A.
93.3
93.3
N.A.
60
60
33.3
N.A.
Percent
Protein Identity:
54.9
N.A.
N.A.
50.8
47
N.A.
Protein Similarity:
71
N.A.
N.A.
67.4
65.1
N.A.
P-Site Identity:
53.3
N.A.
N.A.
53.3
46.6
N.A.
P-Site Similarity:
73.3
N.A.
N.A.
66.6
66.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
8
0
0
0
0
0
8
0
8
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
16
0
0
0
0
8
0
% C
% Asp:
0
0
0
0
0
16
0
0
0
0
24
0
0
0
16
% D
% Glu:
0
8
16
0
85
16
0
0
0
0
39
0
0
0
16
% E
% Phe:
0
0
0
0
0
0
0
16
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
8
0
0
0
24
93
0
0
% G
% His:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
8
0
0
0
0
0
24
0
0
0
0
0
% I
% Lys:
93
16
0
0
0
8
77
0
0
0
8
8
8
0
24
% K
% Leu:
0
0
70
0
0
0
0
0
0
31
16
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
8
0
0
0
0
0
0
0
0
0
70
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% P
% Gln:
0
62
0
0
8
0
8
0
0
8
0
0
0
0
16
% Q
% Arg:
0
0
8
0
0
0
8
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
0
0
54
0
0
0
0
8
0
0
0
24
% S
% Thr:
0
8
0
0
0
8
0
0
77
8
0
0
0
0
0
% T
% Val:
8
0
0
93
0
0
0
0
0
31
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
8
0
0
77
0
0
0
0
0
93
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _