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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
POLD1
All Species:
26.97
Human Site:
T446
Identified Species:
49.44
UniProt:
P28340
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P28340
NP_002682.2
1107
123631
T446
K
Q
T
G
R
R
D
T
K
V
V
S
M
V
G
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001116065
1327
147636
T446
K
Q
T
G
R
R
D
T
K
V
V
S
M
V
G
Dog
Lupus familis
XP_851285
1107
123714
S446
K
Q
T
G
R
R
D
S
K
V
V
S
M
V
G
Cat
Felis silvestris
Mouse
Mus musculus
P52431
1105
123765
S444
R
Q
V
G
R
R
D
S
K
V
I
S
M
V
G
Rat
Rattus norvegicus
O54747
1103
123583
S442
R
Q
V
G
R
R
D
S
K
V
V
S
M
V
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001087694
1109
125430
N451
K
Q
M
G
R
R
E
N
K
V
I
N
T
E
G
Zebra Danio
Brachydanio rerio
NP_001034899
1105
124931
N450
K
Q
M
G
R
R
E
N
K
T
I
N
M
E
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P54358
1092
124887
N430
K
Q
M
G
R
R
E
N
Q
Y
V
N
F
E
G
Honey Bee
Apis mellifera
XP_623795
1105
126747
N447
K
Q
M
G
R
R
E
N
K
S
I
N
F
E
G
Nematode Worm
Caenorhab. elegans
P90829
1081
120811
N416
K
Q
M
G
S
R
V
N
K
S
I
D
I
H
G
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
XP_002307042
1081
121993
S426
R
Q
Y
G
T
R
E
S
K
E
V
T
V
E
G
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9LVN7
1081
121718
S440
R
Q
Q
G
I
R
E
S
K
E
T
T
I
E
G
Baker's Yeast
Sacchar. cerevisiae
P15436
1097
124572
T451
K
A
Y
G
T
R
E
T
K
N
V
N
I
D
G
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
80.6
94.1
N.A.
89.4
89.8
N.A.
N.A.
N.A.
70.9
69.7
N.A.
59.4
58.9
49.6
N.A.
Protein Similarity:
100
N.A.
81.5
96.4
N.A.
94.1
94.3
N.A.
N.A.
N.A.
84
83
N.A.
74.8
74.4
67.9
N.A.
P-Site Identity:
100
N.A.
100
93.3
N.A.
73.3
80
N.A.
N.A.
N.A.
53.3
53.3
N.A.
46.6
46.6
40
N.A.
P-Site Similarity:
100
N.A.
100
100
N.A.
93.3
93.3
N.A.
N.A.
N.A.
73.3
73.3
N.A.
66.6
66.6
53.3
N.A.
Percent
Protein Identity:
54.9
N.A.
N.A.
50.8
47
N.A.
Protein Similarity:
71
N.A.
N.A.
67.4
65.1
N.A.
P-Site Identity:
40
N.A.
N.A.
33.3
46.6
N.A.
P-Site Similarity:
73.3
N.A.
N.A.
66.6
66.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
39
0
0
0
0
8
0
8
0
% D
% Glu:
0
0
0
0
0
0
54
0
0
16
0
0
0
47
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
16
0
0
% F
% Gly:
0
0
0
100
0
0
0
0
0
0
0
0
0
0
100
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% H
% Ile:
0
0
0
0
8
0
0
0
0
0
39
0
24
0
0
% I
% Lys:
70
0
0
0
0
0
0
0
93
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% L
% Met:
0
0
39
0
0
0
0
0
0
0
0
0
47
0
0
% M
% Asn:
0
0
0
0
0
0
0
39
0
8
0
39
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
93
8
0
0
0
0
0
8
0
0
0
0
0
0
% Q
% Arg:
31
0
0
0
70
100
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
0
8
0
0
39
0
16
0
39
0
0
0
% S
% Thr:
0
0
24
0
16
0
0
24
0
8
8
16
8
0
0
% T
% Val:
0
0
16
0
0
0
8
0
0
47
54
0
8
39
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
16
0
0
0
0
0
0
8
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _