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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
POLD1
All Species:
28.48
Human Site:
S434
Identified Species:
52.22
UniProt:
P28340
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P28340
NP_002682.2
1107
123631
S434
L
C
S
N
I
R
D
S
S
F
Q
S
K
Q
T
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001116065
1327
147636
S434
L
R
S
N
I
R
D
S
S
F
Q
S
K
Q
T
Dog
Lupus familis
XP_851285
1107
123714
S434
L
R
S
N
I
R
D
S
S
F
Q
S
K
Q
T
Cat
Felis silvestris
Mouse
Mus musculus
P52431
1105
123765
S432
L
R
S
N
I
R
D
S
S
F
Q
S
R
Q
V
Rat
Rattus norvegicus
O54747
1103
123583
S430
L
R
S
N
I
R
D
S
S
F
Q
S
R
Q
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001087694
1109
125430
S439
L
K
S
V
I
R
D
S
S
F
Q
S
K
Q
M
Zebra Danio
Brachydanio rerio
NP_001034899
1105
124931
S438
C
K
S
V
L
K
D
S
S
F
Q
S
K
Q
M
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P54358
1092
124887
Q418
I
R
S
V
I
K
E
Q
M
L
Q
S
K
Q
M
Honey Bee
Apis mellifera
XP_623795
1105
126747
Q435
I
K
S
V
I
K
T
Q
V
L
Q
S
K
Q
M
Nematode Worm
Caenorhab. elegans
P90829
1081
120811
A404
K
G
S
V
V
R
D
A
A
I
S
S
K
Q
M
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
XP_002307042
1081
121993
A414
S
R
V
R
I
K
D
A
T
F
S
S
R
Q
Y
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9LVN7
1081
121718
S428
S
R
V
R
V
R
D
S
T
F
S
S
R
Q
Q
Baker's Yeast
Sacchar. cerevisiae
P15436
1097
124572
S439
V
K
Q
E
I
K
E
S
V
F
S
S
K
A
Y
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
80.6
94.1
N.A.
89.4
89.8
N.A.
N.A.
N.A.
70.9
69.7
N.A.
59.4
58.9
49.6
N.A.
Protein Similarity:
100
N.A.
81.5
96.4
N.A.
94.1
94.3
N.A.
N.A.
N.A.
84
83
N.A.
74.8
74.4
67.9
N.A.
P-Site Identity:
100
N.A.
93.3
93.3
N.A.
80
80
N.A.
N.A.
N.A.
80
60
N.A.
40
40
40
N.A.
P-Site Similarity:
100
N.A.
93.3
93.3
N.A.
86.6
86.6
N.A.
N.A.
N.A.
80
73.3
N.A.
60
53.3
60
N.A.
Percent
Protein Identity:
54.9
N.A.
N.A.
50.8
47
N.A.
Protein Similarity:
71
N.A.
N.A.
67.4
65.1
N.A.
P-Site Identity:
33.3
N.A.
N.A.
40
33.3
N.A.
P-Site Similarity:
60
N.A.
N.A.
60
53.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
16
8
0
0
0
0
8
0
% A
% Cys:
8
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
77
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
8
0
0
16
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
77
0
0
0
0
0
% F
% Gly:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
16
0
0
0
77
0
0
0
0
8
0
0
0
0
0
% I
% Lys:
8
31
0
0
0
39
0
0
0
0
0
0
70
0
0
% K
% Leu:
47
0
0
0
8
0
0
0
0
16
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
8
0
0
0
0
0
39
% M
% Asn:
0
0
0
39
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
8
0
0
0
0
16
0
0
70
0
0
93
8
% Q
% Arg:
0
54
0
16
0
62
0
0
0
0
0
0
31
0
0
% R
% Ser:
16
0
77
0
0
0
0
70
54
0
31
100
0
0
0
% S
% Thr:
0
0
0
0
0
0
8
0
16
0
0
0
0
0
24
% T
% Val:
8
0
16
39
16
0
0
0
16
0
0
0
0
0
16
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
16
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _