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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
NDUFS1
All Species:
37.27
Human Site:
S448
Identified Species:
63.08
UniProt:
P28331
Number Species:
13
Phosphosite Substitution
Charge Score:
0.15
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P28331
NP_004997.4
727
79468
S448
T
Y
D
H
L
G
D
S
P
K
I
L
Q
D
I
Chimpanzee
Pan troglodytes
Q0MQG2
727
79504
S448
T
Y
D
H
L
G
D
S
P
K
I
L
Q
D
I
Rhesus Macaque
Macaca mulatta
XP_001105760
724
79061
G445
T
Y
Q
P
D
H
H
G
E
T
P
P
L
L
P
Dog
Lupus familis
XP_536039
727
79660
S448
R
Y
D
H
L
G
D
S
P
K
I
L
Q
D
I
Cat
Felis silvestris
Mouse
Mus musculus
Q91VD9
727
79730
S448
R
Y
D
H
L
G
D
S
P
K
I
L
Q
D
I
Rat
Rattus norvegicus
Q66HF1
727
79394
S448
R
Y
D
H
L
G
D
S
P
K
I
L
Q
D
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_001006518
728
79558
S449
T
Y
D
H
L
G
E
S
P
Q
I
L
Q
D
I
Frog
Xenopus laevis
NP_001080308
727
79557
S448
T
Y
D
N
L
G
E
S
P
Q
I
L
K
E
I
Zebra Danio
Brachydanio rerio
NP_001007766
731
79415
T452
S
Y
N
H
L
G
E
T
T
Q
V
L
Q
D
I
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q94511
731
78612
D459
D
H
E
N
L
G
A
D
A
A
L
V
K
D
V
Honey Bee
Apis mellifera
NP_001165875
727
80351
S454
D
Y
E
H
L
G
Q
S
P
E
I
I
T
Q
L
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_801919
730
79428
S458
D
Y
E
H
I
G
D
S
T
A
V
L
K
Q
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9FGI6
748
81507
G488
D
C
K
H
L
G
T
G
P
D
T
L
K
E
I
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
P24918
744
81583
D457
E
F
E
H
L
G
T
D
H
A
A
L
Q
K
A
Conservation
Percent
Protein Identity:
100
99.4
96
97.8
N.A.
94.2
94.9
N.A.
N.A.
86.6
85.2
80.7
N.A.
62.1
64.7
N.A.
71.5
Protein Similarity:
100
99.8
97.1
99.4
N.A.
97.8
97.8
N.A.
N.A.
93.5
93.6
91.5
N.A.
76.8
78.2
N.A.
83.9
P-Site Identity:
100
100
13.3
93.3
N.A.
93.3
93.3
N.A.
N.A.
86.6
66.6
53.3
N.A.
20
46.6
N.A.
40
P-Site Similarity:
100
100
13.3
93.3
N.A.
93.3
93.3
N.A.
N.A.
100
100
93.3
N.A.
66.6
73.3
N.A.
73.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
52.9
N.A.
53.2
Protein Similarity:
N.A.
N.A.
N.A.
68.1
N.A.
68.6
P-Site Identity:
N.A.
N.A.
N.A.
40
N.A.
33.3
P-Site Similarity:
N.A.
N.A.
N.A.
53.3
N.A.
46.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
8
0
8
22
8
0
0
0
8
% A
% Cys:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
29
0
50
0
8
0
43
15
0
8
0
0
0
58
0
% D
% Glu:
8
0
29
0
0
0
22
0
8
8
0
0
0
15
0
% E
% Phe:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
93
0
15
0
0
0
0
0
0
0
% G
% His:
0
8
0
79
0
8
8
0
8
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
8
0
0
0
0
0
58
8
0
0
65
% I
% Lys:
0
0
8
0
0
0
0
0
0
36
0
0
29
8
0
% K
% Leu:
0
0
0
0
86
0
0
0
0
0
8
79
8
8
15
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
8
15
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
8
0
0
0
0
65
0
8
8
0
0
8
% P
% Gln:
0
0
8
0
0
0
8
0
0
22
0
0
58
15
0
% Q
% Arg:
22
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
8
0
0
0
0
0
0
65
0
0
0
0
0
0
0
% S
% Thr:
36
0
0
0
0
0
15
8
15
8
8
0
8
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
15
8
0
0
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
79
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _