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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ELK4 All Species: 21.21
Human Site: S269 Identified Species: 46.67
UniProt: P28324 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P28324 NP_001964.2 431 46900 S269 Q E P P R T P S P P L S S H P
Chimpanzee Pan troglodytes A2T762 512 57113 S304 E M K H Y L H S Q A C S V F N
Rhesus Macaque Macaca mulatta XP_001087748 441 47942 S279 Q E P P R T P S P P L S S H P
Dog Lupus familis XP_545691 413 44565 T251 P E P P R T P T P P L S P N P
Cat Felis silvestris
Mouse Mus musculus P41158 430 46849 S268 K E P P R T P S P P L S S N P
Rat Rattus norvegicus NP_001100643 430 46777 S268 Q E P P R T P S P P L S S N P
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001509517 434 46988 P272 T S R S P S P P L S S N P D L
Chicken Gallus gallus XP_417965 448 48405 S286 P P S P P L S S N P D L D I D
Frog Xenopus laevis NP_001079323 406 44792 T245 V S E P T D T T S T A I E I E
Zebra Danio Brachydanio rerio NP_571005 443 48186 S281 S S S P I T D S Q Q L V I D S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus NP_999792 454 49556 L287 R L N G E T K L V S T G G R P
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 22.8 95.6 82.5 N.A. 85.1 86.3 N.A. 82.7 76.3 61 55 N.A. N.A. N.A. N.A. 20.4
Protein Similarity: 100 35.5 95.9 88.8 N.A. 90.7 91.4 N.A. 89.1 84.1 73.7 67 N.A. N.A. N.A. N.A. 38.5
P-Site Identity: 100 13.3 100 73.3 N.A. 86.6 93.3 N.A. 6.6 20 6.6 26.6 N.A. N.A. N.A. N.A. 13.3
P-Site Similarity: 100 20 100 86.6 N.A. 100 100 N.A. 20 20 13.3 26.6 N.A. N.A. N.A. N.A. 20
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 0 10 10 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 10 0 0 0 0 % C
% Asp: 0 0 0 0 0 10 10 0 0 0 10 0 10 19 10 % D
% Glu: 10 46 10 0 10 0 0 0 0 0 0 0 10 0 10 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 10 0 % F
% Gly: 0 0 0 10 0 0 0 0 0 0 0 10 10 0 0 % G
% His: 0 0 0 10 0 0 10 0 0 0 0 0 0 19 0 % H
% Ile: 0 0 0 0 10 0 0 0 0 0 0 10 10 19 0 % I
% Lys: 10 0 10 0 0 0 10 0 0 0 0 0 0 0 0 % K
% Leu: 0 10 0 0 0 19 0 10 10 0 55 10 0 0 10 % L
% Met: 0 10 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 10 0 0 0 0 0 10 0 0 10 0 28 10 % N
% Pro: 19 10 46 73 19 0 55 10 46 55 0 0 19 0 55 % P
% Gln: 28 0 0 0 0 0 0 0 19 10 0 0 0 0 0 % Q
% Arg: 10 0 10 0 46 0 0 0 0 0 0 0 0 10 0 % R
% Ser: 10 28 19 10 0 10 10 64 10 19 10 55 37 0 10 % S
% Thr: 10 0 0 0 10 64 10 19 0 10 10 0 0 0 0 % T
% Val: 10 0 0 0 0 0 0 0 10 0 0 10 10 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 10 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _