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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ELK4
All Species:
12.42
Human Site:
S257
Identified Species:
27.33
UniProt:
P28324
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P28324
NP_001964.2
431
46900
S257
A
T
T
P
P
I
S
S
I
P
P
L
Q
E
P
Chimpanzee
Pan troglodytes
A2T762
512
57113
S292
F
T
S
S
S
C
F
S
F
N
P
E
E
M
K
Rhesus Macaque
Macaca mulatta
XP_001087748
441
47942
S267
A
T
T
P
P
I
S
S
I
P
P
L
Q
E
P
Dog
Lupus familis
XP_545691
413
44565
V239
A
A
P
P
I
S
S
V
S
P
S
V
P
E
P
Cat
Felis silvestris
Mouse
Mus musculus
P41158
430
46849
T256
P
T
P
P
V
P
S
T
P
L
P
L
K
E
P
Rat
Rattus norvegicus
NP_001100643
430
46777
I256
P
T
P
P
V
P
S
I
P
L
P
L
Q
E
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509517
434
46988
P260
S
P
E
S
S
L
S
P
P
L
G
E
T
S
R
Chicken
Gallus gallus
XP_417965
448
48405
Q274
S
S
V
S
P
V
L
Q
V
P
S
T
P
P
S
Frog
Xenopus laevis
NP_001079323
406
44792
S233
S
T
I
S
P
L
A
S
S
V
S
T
V
S
E
Zebra Danio
Brachydanio rerio
NP_571005
443
48186
S269
P
S
V
L
H
H
S
S
Q
S
P
S
S
S
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
NP_999792
454
49556
Y275
T
V
N
V
Q
E
V
Y
I
T
E
A
R
L
N
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
22.8
95.6
82.5
N.A.
85.1
86.3
N.A.
82.7
76.3
61
55
N.A.
N.A.
N.A.
N.A.
20.4
Protein Similarity:
100
35.5
95.9
88.8
N.A.
90.7
91.4
N.A.
89.1
84.1
73.7
67
N.A.
N.A.
N.A.
N.A.
38.5
P-Site Identity:
100
20
100
40
N.A.
46.6
53.3
N.A.
6.6
13.3
20
20
N.A.
N.A.
N.A.
N.A.
6.6
P-Site Similarity:
100
33.3
100
46.6
N.A.
60
53.3
N.A.
20
40
40
26.6
N.A.
N.A.
N.A.
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
28
10
0
0
0
0
10
0
0
0
0
10
0
0
0
% A
% Cys:
0
0
0
0
0
10
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
10
0
0
10
0
0
0
0
10
19
10
46
10
% E
% Phe:
10
0
0
0
0
0
10
0
10
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
10
0
0
0
0
% G
% His:
0
0
0
0
10
10
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
10
0
10
19
0
10
28
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
10
% K
% Leu:
0
0
0
10
0
19
10
0
0
28
0
37
0
10
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
0
% M
% Asn:
0
0
10
0
0
0
0
0
0
10
0
0
0
0
10
% N
% Pro:
28
10
28
46
37
19
0
10
28
37
55
0
19
10
46
% P
% Gln:
0
0
0
0
10
0
0
10
10
0
0
0
28
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
10
% R
% Ser:
28
19
10
37
19
10
64
46
19
10
28
10
10
28
19
% S
% Thr:
10
55
19
0
0
0
0
10
0
10
0
19
10
0
0
% T
% Val:
0
10
19
10
19
10
10
10
10
10
0
10
10
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
10
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _