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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ELK4
All Species:
13.64
Human Site:
S149
Identified Species:
30
UniProt:
P28324
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.2
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P28324
NP_001964.2
431
46900
S149
I
H
S
G
L
Y
S
S
F
T
L
N
S
L
N
Chimpanzee
Pan troglodytes
A2T762
512
57113
G184
S
G
Q
E
S
S
N
G
T
D
R
K
T
E
L
Rhesus Macaque
Macaca mulatta
XP_001087748
441
47942
S159
I
H
S
G
L
Y
S
S
F
T
L
N
S
L
N
Dog
Lupus familis
XP_545691
413
44565
P131
G
R
E
K
P
P
Q
P
G
A
R
A
S
S
R
Cat
Felis silvestris
Mouse
Mus musculus
P41158
430
46849
S148
I
H
S
G
L
Y
S
S
F
T
L
N
S
L
N
Rat
Rattus norvegicus
NP_001100643
430
46777
S148
I
H
S
G
L
Y
S
S
F
T
L
N
S
L
N
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509517
434
46988
L152
G
L
Y
S
S
F
T
L
N
S
L
N
S
S
N
Chicken
Gallus gallus
XP_417965
448
48405
K166
V
K
L
F
R
S
I
K
I
E
N
P
A
E
K
Frog
Xenopus laevis
NP_001079323
406
44792
K125
W
E
K
K
N
Y
D
K
E
Q
A
P
A
P
P
Zebra Danio
Brachydanio rerio
NP_571005
443
48186
L161
T
S
F
A
L
T
S
L
Q
S
G
T
Q
L
F
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
NP_999792
454
49556
P167
V
K
T
E
N
K
I
P
F
R
V
K
M
E
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
22.8
95.6
82.5
N.A.
85.1
86.3
N.A.
82.7
76.3
61
55
N.A.
N.A.
N.A.
N.A.
20.4
Protein Similarity:
100
35.5
95.9
88.8
N.A.
90.7
91.4
N.A.
89.1
84.1
73.7
67
N.A.
N.A.
N.A.
N.A.
38.5
P-Site Identity:
100
0
100
6.6
N.A.
100
100
N.A.
26.6
0
6.6
20
N.A.
N.A.
N.A.
N.A.
6.6
P-Site Similarity:
100
13.3
100
6.6
N.A.
100
100
N.A.
46.6
13.3
13.3
26.6
N.A.
N.A.
N.A.
N.A.
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
10
0
0
0
0
0
10
10
10
19
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
10
0
0
10
0
0
0
0
0
% D
% Glu:
0
10
10
19
0
0
0
0
10
10
0
0
0
28
0
% E
% Phe:
0
0
10
10
0
10
0
0
46
0
0
0
0
0
10
% F
% Gly:
19
10
0
37
0
0
0
10
10
0
10
0
0
0
0
% G
% His:
0
37
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
37
0
0
0
0
0
19
0
10
0
0
0
0
0
0
% I
% Lys:
0
19
10
19
0
10
0
19
0
0
0
19
0
0
10
% K
% Leu:
0
10
10
0
46
0
0
19
0
0
46
0
0
46
10
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% M
% Asn:
0
0
0
0
19
0
10
0
10
0
10
46
0
0
46
% N
% Pro:
0
0
0
0
10
10
0
19
0
0
0
19
0
10
10
% P
% Gln:
0
0
10
0
0
0
10
0
10
10
0
0
10
0
0
% Q
% Arg:
0
10
0
0
10
0
0
0
0
10
19
0
0
0
10
% R
% Ser:
10
10
37
10
19
19
46
37
0
19
0
0
55
19
10
% S
% Thr:
10
0
10
0
0
10
10
0
10
37
0
10
10
0
0
% T
% Val:
19
0
0
0
0
0
0
0
0
0
10
0
0
0
0
% V
% Trp:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
10
0
0
46
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _