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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ITPKB
All Species:
12.42
Human Site:
Y854
Identified Species:
24.85
UniProt:
P27987
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P27987
NP_002212.3
946
102376
Y854
N
H
N
I
L
I
A
Y
R
D
R
L
K
A
I
Chimpanzee
Pan troglodytes
XP_001141610
946
102163
Y854
N
R
N
I
L
I
A
Y
R
D
R
L
K
A
I
Rhesus Macaque
Macaca mulatta
XP_001089824
939
101522
D849
Q
V
A
I
A
Y
R
D
R
L
K
A
I
R
T
Dog
Lupus familis
XP_547504
936
98978
Y844
N
R
N
I
L
I
A
Y
R
D
R
L
K
D
I
Cat
Felis silvestris
Mouse
Mus musculus
Q7TS72
678
74474
L594
L
R
K
Y
V
A
R
L
E
D
L
R
E
T
L
Rat
Rattus norvegicus
P42335
934
101801
Y842
N
Q
N
I
L
I
A
Y
R
D
R
L
K
A
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513057
370
41159
S286
M
Q
W
R
E
T
I
S
S
T
A
T
L
G
F
Chicken
Gallus gallus
XP_415039
637
69972
R553
L
N
R
L
K
G
I
R
A
T
L
E
T
S
P
Frog
Xenopus laevis
NP_001088157
516
58252
L432
L
R
K
Y
L
V
R
L
K
E
L
R
T
A
L
Zebra Danio
Brachydanio rerio
XP_691475
657
73298
I573
Y
L
N
R
L
K
E
I
R
D
T
L
E
M
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_572875
669
73198
I585
H
D
Q
T
H
A
S
I
W
L
I
D
F
A
K
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_795627
356
40840
R272
I
R
R
L
K
A
I
R
A
T
L
E
A
S
P
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.5
93.6
73.7
N.A.
34.4
76.2
N.A.
31.7
51.1
32.6
44.9
N.A.
32.6
N.A.
N.A.
25.2
Protein Similarity:
100
99
95.1
79.1
N.A.
46.7
80.9
N.A.
34.1
57
41.6
54.1
N.A.
46.2
N.A.
N.A.
30
P-Site Identity:
100
93.3
13.3
86.6
N.A.
6.6
93.3
N.A.
0
0
13.3
33.3
N.A.
6.6
N.A.
N.A.
0
P-Site Similarity:
100
93.3
20
86.6
N.A.
26.6
93.3
N.A.
0
20
40
40
N.A.
20
N.A.
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
9
0
9
25
34
0
17
0
9
9
9
42
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
9
0
0
0
0
0
9
0
50
0
9
0
9
0
% D
% Glu:
0
0
0
0
9
0
9
0
9
9
0
17
17
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
9
0
9
% F
% Gly:
0
0
0
0
0
9
0
0
0
0
0
0
0
9
0
% G
% His:
9
9
0
0
9
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
9
0
0
42
0
34
25
17
0
0
9
0
9
0
34
% I
% Lys:
0
0
17
0
17
9
0
0
9
0
9
0
34
0
9
% K
% Leu:
25
9
0
17
50
0
0
17
0
17
34
42
9
0
17
% L
% Met:
9
0
0
0
0
0
0
0
0
0
0
0
0
9
0
% M
% Asn:
34
9
42
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
17
% P
% Gln:
9
17
9
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
42
17
17
0
0
25
17
50
0
34
17
0
9
0
% R
% Ser:
0
0
0
0
0
0
9
9
9
0
0
0
0
17
9
% S
% Thr:
0
0
0
9
0
9
0
0
0
25
9
9
17
9
9
% T
% Val:
0
9
0
0
9
9
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
9
0
0
0
0
0
9
0
0
0
0
0
0
% W
% Tyr:
9
0
0
17
0
9
0
34
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _