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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ITPKB
All Species:
20.61
Human Site:
T822
Identified Species:
41.21
UniProt:
P27987
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.18
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P27987
NP_002212.3
946
102376
T822
G
I
K
K
E
D
G
T
V
N
R
D
F
K
K
Chimpanzee
Pan troglodytes
XP_001141610
946
102163
T822
G
I
K
K
E
D
G
T
V
N
R
D
F
K
K
Rhesus Macaque
Macaca mulatta
XP_001089824
939
101522
T817
G
I
K
K
E
D
G
T
V
N
R
D
F
K
K
Dog
Lupus familis
XP_547504
936
98978
S812
G
I
K
K
E
D
G
S
V
N
R
D
F
K
K
Cat
Felis silvestris
Mouse
Mus musculus
Q7TS72
678
74474
N562
A
D
G
T
C
N
T
N
F
K
K
T
Q
A
L
Rat
Rattus norvegicus
P42335
934
101801
S810
G
I
K
K
E
D
G
S
V
N
R
D
F
K
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513057
370
41159
K254
L
R
K
D
M
Y
Q
K
M
I
E
V
D
P
E
Chicken
Gallus gallus
XP_415039
637
69972
T521
V
N
R
D
F
K
K
T
R
T
K
E
Q
V
T
Frog
Xenopus laevis
NP_001088157
516
58252
N400
A
D
G
S
C
D
T
N
F
K
K
T
R
C
K
Zebra Danio
Brachydanio rerio
XP_691475
657
73298
K541
T
V
N
R
D
F
K
K
T
K
T
R
E
Q
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_572875
669
73198
A553
R
Y
I
Q
R
L
R
A
I
R
A
T
L
A
V
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_795627
356
40840
T240
S
S
R
D
F
K
T
T
K
T
R
D
Q
I
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.5
93.6
73.7
N.A.
34.4
76.2
N.A.
31.7
51.1
32.6
44.9
N.A.
32.6
N.A.
N.A.
25.2
Protein Similarity:
100
99
95.1
79.1
N.A.
46.7
80.9
N.A.
34.1
57
41.6
54.1
N.A.
46.2
N.A.
N.A.
30
P-Site Identity:
100
100
100
93.3
N.A.
0
93.3
N.A.
6.6
6.6
13.3
0
N.A.
0
N.A.
N.A.
20
P-Site Similarity:
100
100
100
100
N.A.
13.3
100
N.A.
20
26.6
20
26.6
N.A.
13.3
N.A.
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
17
0
0
0
0
0
0
9
0
0
9
0
0
17
0
% A
% Cys:
0
0
0
0
17
0
0
0
0
0
0
0
0
9
0
% C
% Asp:
0
17
0
25
9
50
0
0
0
0
0
50
9
0
0
% D
% Glu:
0
0
0
0
42
0
0
0
0
0
9
9
9
0
9
% E
% Phe:
0
0
0
0
17
9
0
0
17
0
0
0
42
0
0
% F
% Gly:
42
0
17
0
0
0
42
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
42
9
0
0
0
0
0
9
9
0
0
0
9
0
% I
% Lys:
0
0
50
42
0
17
17
17
9
25
25
0
0
42
50
% K
% Leu:
9
0
0
0
0
9
0
0
0
0
0
0
9
0
9
% L
% Met:
0
0
0
0
9
0
0
0
9
0
0
0
0
0
0
% M
% Asn:
0
9
9
0
0
9
0
17
0
42
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
9
0
% P
% Gln:
0
0
0
9
0
0
9
0
0
0
0
0
25
9
0
% Q
% Arg:
9
9
17
9
9
0
9
0
9
9
50
9
9
0
0
% R
% Ser:
9
9
0
9
0
0
0
17
0
0
0
0
0
0
9
% S
% Thr:
9
0
0
9
0
0
25
42
9
17
9
25
0
0
9
% T
% Val:
9
9
0
0
0
0
0
0
42
0
0
9
0
9
17
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
9
0
0
0
9
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _