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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ITPKB
All Species:
19.39
Human Site:
T757
Identified Species:
38.79
UniProt:
P27987
Number Species:
11
Phosphosite Substitution
Charge Score:
0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P27987
NP_002212.3
946
102376
T757
T
Y
L
E
E
E
L
T
K
A
R
K
K
P
S
Chimpanzee
Pan troglodytes
XP_001141610
946
102163
T757
T
Y
L
E
E
E
L
T
K
A
R
K
K
P
S
Rhesus Macaque
Macaca mulatta
XP_001089824
939
101522
T752
T
Y
L
E
E
E
L
T
K
A
R
K
K
P
S
Dog
Lupus familis
XP_547504
936
98978
T747
T
Y
L
E
E
E
L
T
K
A
R
K
K
P
S
Cat
Felis silvestris
Mouse
Mus musculus
Q7TS72
678
74474
E497
E
E
L
V
K
A
R
E
R
P
K
P
R
K
D
Rat
Rattus norvegicus
P42335
934
101801
T745
T
Y
L
E
E
E
L
T
K
A
R
K
K
P
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513057
370
41159
V189
L
D
R
L
M
T
D
V
L
K
P
F
V
P
A
Chicken
Gallus gallus
XP_415039
637
69972
L456
K
A
R
K
K
P
S
L
R
K
D
M
Y
Q
K
Frog
Xenopus laevis
NP_001088157
516
58252
E335
E
E
L
V
K
A
K
E
K
P
K
L
R
K
D
Zebra Danio
Brachydanio rerio
XP_691475
657
73298
S476
T
K
A
R
K
K
P
S
L
R
A
D
M
Y
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_572875
669
73198
R488
A
K
A
V
T
K
P
R
Y
M
V
W
R
E
T
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_795627
356
40840
L175
K
A
R
E
K
P
K
L
R
K
D
M
Y
Q
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.5
93.6
73.7
N.A.
34.4
76.2
N.A.
31.7
51.1
32.6
44.9
N.A.
32.6
N.A.
N.A.
25.2
Protein Similarity:
100
99
95.1
79.1
N.A.
46.7
80.9
N.A.
34.1
57
41.6
54.1
N.A.
46.2
N.A.
N.A.
30
P-Site Identity:
100
100
100
100
N.A.
6.6
100
N.A.
6.6
0
13.3
6.6
N.A.
0
N.A.
N.A.
6.6
P-Site Similarity:
100
100
100
100
N.A.
33.3
100
N.A.
13.3
20
33.3
26.6
N.A.
20
N.A.
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
9
17
17
0
0
17
0
0
0
42
9
0
0
0
9
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
9
0
0
0
0
9
0
0
0
17
9
0
0
17
% D
% Glu:
17
17
0
50
42
42
0
17
0
0
0
0
0
9
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
9
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
17
17
0
9
42
17
17
0
50
25
17
42
42
17
17
% K
% Leu:
9
0
59
9
0
0
42
17
17
0
0
9
0
0
0
% L
% Met:
0
0
0
0
9
0
0
0
0
9
0
17
9
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
17
17
0
0
17
9
9
0
50
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
17
9
% Q
% Arg:
0
0
25
9
0
0
9
9
25
9
42
0
25
0
0
% R
% Ser:
0
0
0
0
0
0
9
9
0
0
0
0
0
0
42
% S
% Thr:
50
0
0
0
9
9
0
42
0
0
0
0
0
0
9
% T
% Val:
0
0
0
25
0
0
0
9
0
0
9
0
9
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
9
0
0
0
% W
% Tyr:
0
42
0
0
0
0
0
0
9
0
0
0
17
9
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _