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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ITPKB
All Species:
21.52
Human Site:
S604
Identified Species:
43.03
UniProt:
P27987
Number Species:
11
Phosphosite Substitution
Charge Score:
0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P27987
NP_002212.3
946
102376
S604
K
L
S
S
S
S
A
S
S
T
G
F
S
S
S
Chimpanzee
Pan troglodytes
XP_001141610
946
102163
S604
K
L
S
S
S
S
A
S
S
T
G
F
S
S
S
Rhesus Macaque
Macaca mulatta
XP_001089824
939
101522
S599
K
L
S
S
S
S
A
S
S
T
G
F
S
S
S
Dog
Lupus familis
XP_547504
936
98978
S594
K
L
S
S
S
S
A
S
S
T
G
F
S
S
S
Cat
Felis silvestris
Mouse
Mus musculus
Q7TS72
678
74474
G350
R
I
E
G
G
T
G
G
F
S
S
A
S
S
F
Rat
Rattus norvegicus
P42335
934
101801
S592
K
L
S
S
S
S
A
S
S
T
G
F
S
S
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513057
370
41159
G42
R
S
P
F
P
R
E
G
C
C
P
G
N
I
P
Chicken
Gallus gallus
XP_415039
637
69972
D309
S
W
E
E
S
E
E
D
I
S
S
D
P
E
R
Frog
Xenopus laevis
NP_001088157
516
58252
F188
G
L
S
S
A
S
S
F
E
E
S
E
D
D
F
Zebra Danio
Brachydanio rerio
XP_691475
657
73298
S329
S
A
S
S
T
G
F
S
S
S
W
E
E
S
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_572875
669
73198
I341
K
S
S
G
W
R
K
I
R
N
I
V
Q
W
T
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_795627
356
40840
S28
G
L
L
T
E
S
D
S
D
D
S
L
L
D
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.5
93.6
73.7
N.A.
34.4
76.2
N.A.
31.7
51.1
32.6
44.9
N.A.
32.6
N.A.
N.A.
25.2
Protein Similarity:
100
99
95.1
79.1
N.A.
46.7
80.9
N.A.
34.1
57
41.6
54.1
N.A.
46.2
N.A.
N.A.
30
P-Site Identity:
100
100
100
100
N.A.
13.3
100
N.A.
0
6.6
26.6
33.3
N.A.
13.3
N.A.
N.A.
20
P-Site Similarity:
100
100
100
100
N.A.
40
100
N.A.
13.3
13.3
40
46.6
N.A.
20
N.A.
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
9
0
0
9
0
42
0
0
0
0
9
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
9
9
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
9
9
9
9
0
9
9
17
0
% D
% Glu:
0
0
17
9
9
9
17
0
9
9
0
17
9
9
17
% E
% Phe:
0
0
0
9
0
0
9
9
9
0
0
42
0
0
17
% F
% Gly:
17
0
0
17
9
9
9
17
0
0
42
9
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
9
0
0
0
0
0
9
9
0
9
0
0
9
0
% I
% Lys:
50
0
0
0
0
0
9
0
0
0
0
0
0
0
0
% K
% Leu:
0
59
9
0
0
0
0
0
0
0
0
9
9
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
9
0
0
9
0
0
% N
% Pro:
0
0
9
0
9
0
0
0
0
0
9
0
9
0
9
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
9
0
0
% Q
% Arg:
17
0
0
0
0
17
0
0
9
0
0
0
0
0
9
% R
% Ser:
17
17
67
59
50
59
9
59
50
25
34
0
50
59
42
% S
% Thr:
0
0
0
9
9
9
0
0
0
42
0
0
0
0
9
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
9
0
0
0
% V
% Trp:
0
9
0
0
9
0
0
0
0
0
9
0
0
9
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _