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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DCK
All Species:
33.64
Human Site:
Y190
Identified Species:
74
UniProt:
P27707
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P27707
NP_000779.1
260
30519
Y190
E
T
C
L
H
R
I
Y
L
R
G
R
N
E
E
Chimpanzee
Pan troglodytes
XP_517245
260
30524
Y190
E
T
C
L
H
R
M
Y
L
R
G
R
N
E
E
Rhesus Macaque
Macaca mulatta
XP_001093411
635
70321
Y190
E
K
C
L
H
R
I
Y
L
R
G
R
N
E
E
Dog
Lupus familis
XP_539307
260
30216
Y190
E
K
C
L
N
R
I
Y
L
R
G
R
N
E
E
Cat
Felis silvestris
Mouse
Mus musculus
P43346
260
30349
Y190
E
K
C
L
N
R
I
Y
L
R
G
R
N
E
E
Rat
Rattus norvegicus
P48769
260
30388
Y190
E
K
C
L
N
R
I
Y
I
R
G
R
D
E
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509449
260
30247
Y190
E
K
C
L
N
R
I
Y
L
R
G
R
D
E
E
Chicken
Gallus gallus
NP_001006451
257
30355
Y184
E
K
C
L
N
R
I
Y
L
R
G
R
D
E
E
Frog
Xenopus laevis
NP_001088163
263
30867
Y190
E
K
C
L
N
R
V
Y
T
R
G
R
E
E
E
Zebra Danio
Brachydanio rerio
NP_001007057
263
31202
H190
E
R
C
L
E
R
L
H
L
R
G
R
E
E
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9XZT6
250
29070
Q181
C
V
P
L
K
Y
L
Q
E
L
H
E
L
H
E
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.4
39.3
86.9
N.A.
93.4
91.5
N.A.
86.1
79.6
79.4
70.7
N.A.
28.8
N.A.
N.A.
N.A.
Protein Similarity:
100
99.2
40.1
96.1
N.A.
97.3
95.7
N.A.
92.6
90.3
89.3
84
N.A.
53.8
N.A.
N.A.
N.A.
P-Site Identity:
100
93.3
93.3
86.6
N.A.
86.6
73.3
N.A.
80
80
66.6
66.6
N.A.
13.3
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
93.3
93.3
N.A.
93.3
93.3
N.A.
93.3
93.3
80
80
N.A.
20
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
10
0
91
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
28
0
0
% D
% Glu:
91
0
0
0
10
0
0
0
10
0
0
10
19
91
100
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
91
0
0
0
0
% G
% His:
0
0
0
0
28
0
0
10
0
0
10
0
0
10
0
% H
% Ile:
0
0
0
0
0
0
64
0
10
0
0
0
0
0
0
% I
% Lys:
0
64
0
0
10
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
100
0
0
19
0
73
10
0
0
10
0
0
% L
% Met:
0
0
0
0
0
0
10
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
55
0
0
0
0
0
0
0
46
0
0
% N
% Pro:
0
0
10
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
10
0
0
0
0
0
0
0
% Q
% Arg:
0
10
0
0
0
91
0
0
0
91
0
91
0
0
0
% R
% Ser:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% S
% Thr:
0
19
0
0
0
0
0
0
10
0
0
0
0
0
0
% T
% Val:
0
10
0
0
0
0
10
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
10
0
82
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _