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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
RPA1
All Species:
27.58
Human Site:
Y461
Identified Species:
50.56
UniProt:
P27694
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P27694
NP_002936.1
616
68138
Y461
G
Q
G
D
K
P
D
Y
F
S
S
V
A
T
V
Chimpanzee
Pan troglodytes
XP_511254
670
73536
Y515
G
Q
G
D
K
P
D
Y
F
S
S
V
A
T
V
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_548316
616
68389
Y461
G
H
G
D
K
A
D
Y
F
S
S
V
A
T
V
Cat
Felis silvestris
Mouse
Mus musculus
Q8VEE4
623
69019
Y470
G
Q
G
D
K
A
D
Y
F
S
T
V
A
A
V
Rat
Rattus norvegicus
NP_001041308
680
75055
Y519
G
Q
G
D
K
A
D
Y
F
S
T
V
A
T
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507100
619
68389
Y462
G
H
G
D
K
A
E
Y
F
S
C
V
G
T
V
Chicken
Gallus gallus
Q5ZJJ2
614
67982
Y458
G
Q
G
D
K
A
D
Y
F
S
C
V
G
T
I
Frog
Xenopus laevis
Q01588
609
67067
Y452
G
H
G
E
K
A
D
Y
F
T
S
V
A
T
I
Zebra Danio
Brachydanio rerio
Q6NY74
601
66612
V454
F
S
C
I
A
T
I
V
Y
I
R
K
E
N
C
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q24492
603
66606
H452
F
Q
C
K
A
V
V
H
I
V
K
Q
E
N
A
Honey Bee
Apis mellifera
XP_001121722
597
67108
M451
A
T
L
N
M
I
R
M
E
N
A
I
Y
K
A
Nematode Worm
Caenorhab. elegans
Q19537
655
73183
D497
G
K
D
S
D
K
G
D
Y
A
T
V
K
A
M
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P22336
621
70329
F466
G
R
S
E
K
G
D
F
F
S
V
K
A
A
I
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
91.4
N.A.
88.4
N.A.
84.5
78.3
N.A.
82.3
74.6
72.8
63.9
N.A.
43.1
42.3
27
N.A.
Protein Similarity:
100
91.6
N.A.
94.3
N.A.
91.3
83.3
N.A.
91.5
86.1
87.5
80.6
N.A.
62.5
64.4
47.9
N.A.
P-Site Identity:
100
100
N.A.
86.6
N.A.
80
86.6
N.A.
66.6
73.3
66.6
0
N.A.
6.6
0
13.3
N.A.
P-Site Similarity:
100
100
N.A.
86.6
N.A.
86.6
93.3
N.A.
73.3
80
86.6
6.6
N.A.
13.3
26.6
46.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
32.6
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
55.7
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
40
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
66.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
0
0
16
47
0
0
0
8
8
0
54
24
16
% A
% Cys:
0
0
16
0
0
0
0
0
0
0
16
0
0
0
8
% C
% Asp:
0
0
8
54
8
0
62
8
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
16
0
0
8
0
8
0
0
0
16
0
0
% E
% Phe:
16
0
0
0
0
0
0
8
70
0
0
0
0
0
0
% F
% Gly:
77
0
62
0
0
8
8
0
0
0
0
0
16
0
0
% G
% His:
0
24
0
0
0
0
0
8
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
8
0
8
8
0
8
8
0
8
0
0
24
% I
% Lys:
0
8
0
8
70
8
0
0
0
0
8
16
8
8
0
% K
% Leu:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
8
0
0
8
0
0
0
0
0
0
8
% M
% Asn:
0
0
0
8
0
0
0
0
0
8
0
0
0
16
0
% N
% Pro:
0
0
0
0
0
16
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
47
0
0
0
0
0
0
0
0
0
8
0
0
0
% Q
% Arg:
0
8
0
0
0
0
8
0
0
0
8
0
0
0
0
% R
% Ser:
0
8
8
8
0
0
0
0
0
62
31
0
0
0
0
% S
% Thr:
0
8
0
0
0
8
0
0
0
8
24
0
0
54
0
% T
% Val:
0
0
0
0
0
8
8
8
0
8
8
70
0
0
47
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
62
16
0
0
0
8
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _