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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
RPA1
All Species:
20.3
Human Site:
T297
Identified Species:
37.22
UniProt:
P27694
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P27694
NP_002936.1
616
68138
T297
E
D
D
H
H
L
P
T
V
Q
F
D
F
T
G
Chimpanzee
Pan troglodytes
XP_511254
670
73536
T351
E
D
D
R
H
L
P
T
V
Q
F
D
F
T
G
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_548316
616
68389
T297
E
D
G
H
H
L
P
T
V
Q
F
D
F
T
G
Cat
Felis silvestris
Mouse
Mus musculus
Q8VEE4
623
69019
T306
E
D
G
H
H
L
P
T
V
Q
F
D
F
T
G
Rat
Rattus norvegicus
NP_001041308
680
75055
F355
W
G
E
D
A
D
K
F
D
G
S
R
Q
P
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507100
619
68389
T297
E
D
A
H
H
L
P
T
V
Q
F
D
F
T
G
Chicken
Gallus gallus
Q5ZJJ2
614
67982
S294
D
D
A
Q
H
L
P
S
V
Q
F
D
F
V
S
Frog
Xenopus laevis
Q01588
609
67067
M288
D
D
S
A
D
V
P
M
V
Q
F
E
F
V
S
Zebra Danio
Brachydanio rerio
Q6NY74
601
66612
I292
L
Q
C
D
F
V
S
I
A
D
L
E
S
R
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q24492
603
66606
I289
I
K
Y
N
L
V
P
I
S
D
V
S
G
M
E
Honey Bee
Apis mellifera
XP_001121722
597
67108
N288
F
V
S
I
N
D
I
N
K
K
E
Q
N
D
I
Nematode Worm
Caenorhab. elegans
Q19537
655
73183
K335
G
E
L
L
A
A
P
K
L
I
L
K
R
V
K
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P22336
621
70329
P296
C
F
D
E
S
N
V
P
K
T
H
F
N
F
I
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
91.4
N.A.
88.4
N.A.
84.5
78.3
N.A.
82.3
74.6
72.8
63.9
N.A.
43.1
42.3
27
N.A.
Protein Similarity:
100
91.6
N.A.
94.3
N.A.
91.3
83.3
N.A.
91.5
86.1
87.5
80.6
N.A.
62.5
64.4
47.9
N.A.
P-Site Identity:
100
93.3
N.A.
93.3
N.A.
93.3
0
N.A.
93.3
60
40
0
N.A.
6.6
0
6.6
N.A.
P-Site Similarity:
100
93.3
N.A.
93.3
N.A.
93.3
6.6
N.A.
93.3
73.3
60
13.3
N.A.
20
13.3
20
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
32.6
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
55.7
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
16
8
16
8
0
0
8
0
0
0
0
0
0
% A
% Cys:
8
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
16
54
24
16
8
16
0
0
8
16
0
47
0
8
0
% D
% Glu:
39
8
8
8
0
0
0
0
0
0
8
16
0
0
16
% E
% Phe:
8
8
0
0
8
0
0
8
0
0
54
8
54
8
0
% F
% Gly:
8
8
16
0
0
0
0
0
0
8
0
0
8
0
39
% G
% His:
0
0
0
31
47
0
0
0
0
0
8
0
0
0
0
% H
% Ile:
8
0
0
8
0
0
8
16
0
8
0
0
0
0
16
% I
% Lys:
0
8
0
0
0
0
8
8
16
8
0
8
0
0
8
% K
% Leu:
8
0
8
8
8
47
0
0
8
0
16
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
8
0
0
0
0
0
8
0
% M
% Asn:
0
0
0
8
8
8
0
8
0
0
0
0
16
0
0
% N
% Pro:
0
0
0
0
0
0
70
8
0
0
0
0
0
8
0
% P
% Gln:
0
8
0
8
0
0
0
0
0
54
0
8
8
0
0
% Q
% Arg:
0
0
0
8
0
0
0
0
0
0
0
8
8
8
0
% R
% Ser:
0
0
16
0
8
0
8
8
8
0
8
8
8
0
16
% S
% Thr:
0
0
0
0
0
0
0
39
0
8
0
0
0
39
0
% T
% Val:
0
8
0
0
0
24
8
0
54
0
8
0
0
24
8
% V
% Trp:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _