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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
RPA1
All Species:
4.55
Human Site:
S135
Identified Species:
8.33
UniProt:
P27694
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P27694
NP_002936.1
616
68138
S135
A
P
P
A
P
A
A
S
P
A
A
S
S
R
P
Chimpanzee
Pan troglodytes
XP_511254
670
73536
S189
A
P
P
A
P
A
A
S
P
A
A
S
S
R
P
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_548316
616
68389
A135
V
P
S
P
V
S
A
A
N
P
P
A
N
K
P
Cat
Felis silvestris
Mouse
Mus musculus
Q8VEE4
623
69019
A144
V
P
S
P
A
S
A
A
T
P
P
A
S
K
P
Rat
Rattus norvegicus
NP_001041308
680
75055
P173
G
T
Q
S
K
V
V
P
I
A
S
L
T
P
Y
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507100
619
68389
A135
T
P
A
P
G
P
T
A
I
P
P
A
S
K
P
Chicken
Gallus gallus
Q5ZJJ2
614
67982
N132
R
S
S
A
P
T
A
N
A
A
P
N
K
P
Q
Frog
Xenopus laevis
Q01588
609
67067
P130
P
Q
P
A
A
P
A
P
A
S
A
P
A
P
A
Zebra Danio
Brachydanio rerio
Q6NY74
601
66612
R134
T
A
P
A
P
T
A
R
P
L
Q
P
Q
N
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q24492
603
66606
P131
A
A
K
Q
D
L
A
P
K
P
A
V
T
S
N
Honey Bee
Apis mellifera
XP_001121722
597
67108
Q130
G
D
S
K
P
Q
A
Q
I
A
Q
S
A
Q
S
Nematode Worm
Caenorhab. elegans
Q19537
655
73183
N174
M
A
A
D
Y
Q
E
N
M
A
N
P
P
A
A
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P22336
621
70329
E135
P
N
E
T
L
K
D
E
D
I
T
D
S
G
N
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
91.4
N.A.
88.4
N.A.
84.5
78.3
N.A.
82.3
74.6
72.8
63.9
N.A.
43.1
42.3
27
N.A.
Protein Similarity:
100
91.6
N.A.
94.3
N.A.
91.3
83.3
N.A.
91.5
86.1
87.5
80.6
N.A.
62.5
64.4
47.9
N.A.
P-Site Identity:
100
100
N.A.
20
N.A.
26.6
6.6
N.A.
20
26.6
26.6
33.3
N.A.
20
26.6
6.6
N.A.
P-Site Similarity:
100
100
N.A.
53.3
N.A.
53.3
26.6
N.A.
40
40
40
33.3
N.A.
26.6
40
13.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
32.6
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
55.7
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
24
24
16
39
16
16
70
24
16
47
31
24
16
8
16
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
8
0
8
8
0
8
0
8
0
0
8
0
0
0
% D
% Glu:
0
0
8
0
0
0
8
8
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
16
0
0
0
8
0
0
0
0
0
0
0
0
8
8
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
24
8
0
0
0
0
0
% I
% Lys:
0
0
8
8
8
8
0
0
8
0
0
0
8
24
0
% K
% Leu:
0
0
0
0
8
8
0
0
0
8
0
8
0
0
0
% L
% Met:
8
0
0
0
0
0
0
0
8
0
0
0
0
0
0
% M
% Asn:
0
8
0
0
0
0
0
16
8
0
8
8
8
8
16
% N
% Pro:
16
39
31
24
39
16
0
24
24
31
31
24
8
24
39
% P
% Gln:
0
8
8
8
0
16
0
8
0
0
16
0
8
8
8
% Q
% Arg:
8
0
0
0
0
0
0
8
0
0
0
0
0
16
0
% R
% Ser:
0
8
31
8
0
16
0
16
0
8
8
24
39
8
8
% S
% Thr:
16
8
0
8
0
16
8
0
8
0
8
0
16
0
0
% T
% Val:
16
0
0
0
8
8
8
0
0
0
0
8
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
8
0
0
0
0
0
0
0
0
0
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _