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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ATP6V0C All Species: 39.09
Human Site: S37 Identified Species: 53.75
UniProt: P27449 Number Species: 16
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P27449 NP_001685.1 155 15736 S37 A A Y G T A K S G T G I A A M
Chimpanzee Pan troglodytes XP_510748 156 15775 S38 A A Y G T A K S G T G I A A M
Rhesus Macaque Macaca mulatta XP_001085529 417 43146 S299 A A Y G T A K S G T G I A A M
Dog Lupus familis XP_537002 155 15683 S37 A A Y G T A K S G T G I A A M
Cat Felis silvestris
Mouse Mus musculus Q91V37 205 21588 T72 A A W G I Y I T G S S I I G G
Rat Rattus norvegicus P63081 155 15789 S37 A A Y G T A K S G T G I A A M
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_001232268 133 13418 P27 A A M S V M R P E L I M K S I
Frog Xenopus laevis NP_001082675 156 15788 S38 A A Y G T A K S G T G I A A M
Zebra Danio Brachydanio rerio NP_991117 153 15480 I39 T A K S G T G I A A M S V M R
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P23380 159 16249 S39 A A Y G T A K S G T G I A A M
Honey Bee Apis mellifera NP_001011570 156 15953 T38 Y G T A K S G T G I A A M S V
Nematode Worm Caenorhab. elegans P34546 161 16391 S40 A A Y G T A K S A V G I C S M
Sea Urchin Strong. purpuratus XP_797801 155 15612 G37 G T A K S G T G V A A M S V M
Poplar Tree Populus trichocarpa
Maize Zea mays Q41773 109 11025
Rice Oryza sativa
Thale Cress Arabidopsis thaliana P59228 165 16624 S37 A A Y G T A K S G V G V A S M
Baker's Yeast Sacchar. cerevisiae P25515 160 16332 I39 T A K S G V G I C A T C V L R
Red Bread Mold Neurospora crassa P31413 161 16311 A40 A K S G V G I A A M G V L R P
Conservation
Percent
Protein Identity: 100 98 35.2 96.7 N.A. 26.8 90.9 N.A. N.A. 81.2 92.3 92.2 N.A. 80.5 80.7 66.4 82.5
Protein Similarity: 100 98.7 36.4 98.7 N.A. 43.9 96.1 N.A. N.A. 83.8 95.5 94.8 N.A. 86.7 87.8 75.1 90.9
P-Site Identity: 100 100 100 100 N.A. 33.3 100 N.A. N.A. 13.3 100 6.6 N.A. 100 6.6 73.3 6.6
P-Site Similarity: 100 100 100 100 N.A. 53.3 100 N.A. N.A. 40 100 6.6 N.A. 100 33.3 80 26.6
Percent
Protein Identity: N.A. 43.2 N.A. 60 68.7 70.1
Protein Similarity: N.A. 50.9 N.A. 76.3 82.5 84.4
P-Site Identity: N.A. 0 N.A. 80 6.6 20
P-Site Similarity: N.A. 0 N.A. 93.3 6.6 33.3
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 71 77 6 6 0 53 0 6 18 18 12 6 48 42 0 % A
% Cys: 0 0 0 0 0 0 0 0 6 0 0 6 6 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 6 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 6 6 0 65 12 12 18 6 59 0 59 0 0 6 6 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 6 0 12 12 0 6 6 53 6 0 6 % I
% Lys: 0 6 12 6 6 0 53 0 0 0 0 0 6 0 0 % K
% Leu: 0 0 0 0 0 0 0 0 0 6 0 0 6 6 0 % L
% Met: 0 0 6 0 0 6 0 0 0 6 6 12 6 6 59 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 6 0 0 0 0 0 0 6 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 0 6 0 0 0 0 0 0 6 12 % R
% Ser: 0 0 6 18 6 6 0 53 0 6 6 6 6 24 0 % S
% Thr: 12 6 6 0 53 6 6 12 0 42 6 0 0 0 0 % T
% Val: 0 0 0 0 12 6 0 0 6 12 0 12 12 6 6 % V
% Trp: 0 0 6 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 6 0 53 0 0 6 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _