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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MARK3
All Species:
4.55
Human Site:
Y129
Identified Species:
9.09
UniProt:
P27448
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.45
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P27448
NP_001122390.1
776
87005
Y129
I
E
T
E
K
T
L
Y
L
I
M
E
Y
A
S
Chimpanzee
Pan troglodytes
XP_510184
737
82858
K117
L
N
H
P
N
I
V
K
L
F
E
V
I
E
T
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_868647
777
86967
Y129
I
E
T
D
K
T
L
Y
L
I
M
E
Y
A
S
Cat
Felis silvestris
Mouse
Mus musculus
Q03141
753
84371
K117
L
N
H
P
N
I
V
K
L
F
E
V
I
E
T
Rat
Rattus norvegicus
Q8VHF0
797
88733
K117
L
N
H
P
N
I
V
K
L
F
E
V
I
E
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508081
736
82480
E115
V
K
L
F
E
V
I
E
T
E
K
T
L
Y
L
Chicken
Gallus gallus
Q9IA88
798
88848
N153
H
R
D
L
K
T
E
N
L
L
L
D
A
N
M
Frog
Xenopus laevis
NP_001084256
725
81522
K117
L
N
H
P
N
I
V
K
L
F
E
V
I
E
T
Zebra Danio
Brachydanio rerio
Q6NSM8
1187
130949
R120
L
R
H
P
H
I
I
R
L
Y
Q
V
M
E
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q9TW45
1192
126331
K231
L
D
H
P
N
I
V
K
L
Y
Q
V
M
E
T
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q38997
535
61163
Baker's Yeast
Sacchar. cerevisiae
P06782
633
72027
H51
S
S
L
A
D
G
A
H
I
G
N
Y
Q
I
V
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
94.7
N.A.
96.4
N.A.
94
89.9
N.A.
90.5
31.4
85.6
26.5
N.A.
N.A.
N.A.
39.8
N.A.
Protein Similarity:
100
94.7
N.A.
97.4
N.A.
95
91.2
N.A.
92.9
50.7
89.5
42.6
N.A.
N.A.
N.A.
51
N.A.
P-Site Identity:
100
6.6
N.A.
93.3
N.A.
6.6
6.6
N.A.
0
20
6.6
6.6
N.A.
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
100
26.6
N.A.
100
N.A.
26.6
26.6
N.A.
26.6
40
26.6
26.6
N.A.
N.A.
N.A.
33.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
27
27.3
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
44
45.8
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
0
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
9
0
0
9
0
0
0
0
0
9
17
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
9
9
9
9
0
0
0
0
0
0
9
0
0
0
% D
% Glu:
0
17
0
9
9
0
9
9
0
9
34
17
0
50
0
% E
% Phe:
0
0
0
9
0
0
0
0
0
34
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
9
0
0
0
9
0
0
0
0
0
% G
% His:
9
0
50
0
9
0
0
9
0
0
0
0
0
0
0
% H
% Ile:
17
0
0
0
0
50
17
0
9
17
0
0
34
9
0
% I
% Lys:
0
9
0
0
25
0
0
42
0
0
9
0
0
0
0
% K
% Leu:
50
0
17
9
0
0
17
0
75
9
9
0
9
0
9
% L
% Met:
0
0
0
0
0
0
0
0
0
0
17
0
17
0
9
% M
% Asn:
0
34
0
0
42
0
0
9
0
0
9
0
0
9
0
% N
% Pro:
0
0
0
50
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
17
0
9
0
0
% Q
% Arg:
0
17
0
0
0
0
0
9
0
0
0
0
0
0
0
% R
% Ser:
9
9
0
0
0
0
0
0
0
0
0
0
0
0
17
% S
% Thr:
0
0
17
0
0
25
0
0
9
0
0
9
0
0
50
% T
% Val:
9
0
0
0
0
9
42
0
0
0
0
50
0
0
9
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
17
0
17
0
9
17
9
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _